(Q44502343)

English

Pharmacokinetics of melagatran and the effect on ex vivo coagulation time in orthopaedic surgery patients receiving subcutaneous melagatran and oral ximelagatran: a population model analysis

scientific article published in January 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Pharmacokinetics of melagatran and the effect on ex vivo coagulation time in orthopaedic surgery patients receiving subcutaneous melagatran and oral ximelagatran: a population model analysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

Mats O Karlsson

3

object named as

Mats O Karlsson

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

Ulf G Eriksson

1

1 reference

Europe PubMed Central

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3 December 2017

Jaap W Mandema

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Lars Frison

4

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Per Olsson Gisleskog

5

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Ulrika Wählby

6

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Bengt Hamrén

7

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

David Gustafsson

8

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Bengt I Eriksson

9

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

publication date

1 January 2003

1 reference

Europe PubMed Central

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3 December 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

42

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

7

1 reference

Europe PubMed Central

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3 December 2017

687-701

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.2165/00003088-200342070-00006

0 references

A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibiti

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effect of two low molecular weight thrombin inhibitors and a low-molecular weight heparin in a caval vein thrombosis model in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of melagatran, a novel synthetic LMW thrombin inhibitor, in patients with acute DVT

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New anticoagulant drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prophylaxis of venous thromboembolism with subcutaneous melagatran in total hip or total knee replacement: results from Phase II studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of melagatran, a new low-molecular-weight thrombin inhibitor, on thrombin and fibrinolytic enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population modelling of the effect of inogatran, at thrombin inhibitor, on ex vivo coagulation time (APTT) in healthy subjects and patients with coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bivalirudin pharmacokinetics and pharmacodynamics: effect of renal function, dose, and gender

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of melagatran, a novel, direct thrombin inhibitor, in human plasma and urine by liquid chromatography-mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of creatinine clearance from serum creatinine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melagatran, an oral active-site inhibitor of thrombin, prevents or delays formation of electrically induced occlusive thrombus in the canine coronary artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of ximelagatran, a novel oral direct thrombin inhibitor, in young healthy male subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thrombin generation by the oral direct thrombin inhibitor ximelagatran in shed blood from healthy male subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ximelagatran and melagatran compared with dalteparin for prevention of venous thromboembolism after total hip or knee replacement: the METHRO II randomised trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/12844328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200342070-00006

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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