(Q44442558)

3 December 2017

Metformin has direct effects on human ovarian steroidogenesis (English)

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3 December 2017

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Rebecca Mansfield

1

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3 December 2017

Ray Galea

2

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3 December 2017

Mark Brincat

3

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3 December 2017

David Hole

4

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3 December 2017

Helen Mason

5

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3 December 2017

language of work or name

English

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publication date

1 April 2003

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full work available at URL

3 December 2017

http://www.fertstert.org/article/S0015028202049257/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12749437

https://api.elsevier.com/content/article/PII:S0015028202049257?httpAccept=text/xml

2 January 2024

1 reference

https://api.crossref.org/works/10.1016/S0015-0282(02)04925-7

https://api.elsevier.com/content/article/PII:S0015028202049257?httpAccept=text/plain

2 January 2024

1 reference

https://api.crossref.org/works/10.1016/S0015-0282(02)04925-7

2 January 2024

published in

Fertility and Sterility

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3 December 2017

79

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3 December 2017

956-962

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3 December 2017

4

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Polycystic ovary syndrome

3 December 2017

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https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Heterogeneity of the polycystic ovary syndrome: clinical, endocrine and ultrasound features in 556 patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Insulin resistance in nonobese patients with polycystic ovarian disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Polycystic ovary syndrome: clinical aspects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Insulin-lowering medications in polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

The polycystic ovary syndrome: treatment with insulin sensitizing agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Endocrine and metabolic effects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: a randomized study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin therapy decreases hyperandrogenism and hyperinsulinemia in women with polycystic ovary syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin treatment reduces ovarian cytochrome P-450c17alpha response to human chorionic gonadotrophin in women with insulin resistance-related polycystic ovary syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Effects of the insulin sensitizing drug metformin on ovarian function, follicular growth and ovulation rate in obese women with oligomenorrhoea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin therapy improves ovulatory rates, cervical scores, and pregnancy rates in clomiphene citrate-resistant women with polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Inhibition of oestradiol production by epidermal growth factor in human granulosa cells of normal and polycystic ovaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Prostaglandin F2 alpha activates protein kinase C in human ovarian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Effects of dose of LH on androgen production and luteinization of ovine theca cells cultured in a serum-free system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3beta -hydroxysteroid dehydrogenase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Metformin directly inhibits androgen production in human thecal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Ovarian steroidogenic response to human chorionic gonadotrophin in obese women with polycystic ovary syndrome: effect of metformin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Effects of metformin on adrenal steroidogenesis in women with polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0015-0282%2802%2904925-7

Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome

7 January 2021

6

1 reference

https://api.crossref.org/works/10.1016/S0015-0282(02)04925-7

Sensitization to insulin induces ovulation in nonobese adolescents with anovulatory hyperandrogenism.

2 January 2024

25

1 reference

https://api.crossref.org/works/10.1016/S0015-0282(02)04925-7

Troglitazone inhibits progesterone production in porcine granulosa cells

2 January 2024

32

1 reference

https://api.crossref.org/works/10.1016/S0015-0282(02)04925-7

2 January 2024

Identifiers

1 reference

3 December 2017

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