(Q44445731)

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N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression

scientific article published on May 15, 2003

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Europe PubMed Central

PubMed publication ID

3 December 2017

N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression (English)

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Europe PubMed Central

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3 December 2017

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10.1016/S0006-2952(03)00147-3

https://api.crossref.org/works/10.1016/S0006-2952(03)00147-3

3 January 2024

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10.1016/S0006-2952(03)00147-3

https://api.crossref.org/works/10.1016/S0006-2952(03)00147-3

3 January 2024

author name string

Manuel Rieber

1

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3 December 2017

Mary Strasberg Rieber

2

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3 December 2017

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publication date

1 May 2003

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3 December 2017

15 May 2003

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12754095

3 January 2024

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https://api.elsevier.com/content/article/PII:S0006295203001473?httpAccept=text/xml

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10.1016/S0006-2952(03)00147-3

https://api.crossref.org/works/10.1016/S0006-2952(03)00147-3

3 January 2024

https://api.elsevier.com/content/article/PII:S0006295203001473?httpAccept=text/plain

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10.1016/S0006-2952(03)00147-3

https://api.crossref.org/works/10.1016/S0006-2952(03)00147-3

3 January 2024

Biochemical Pharmacology

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Europe PubMed Central

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3 December 2017

65

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Europe PubMed Central

PubMed publication ID

3 December 2017

10

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Europe PubMed Central

PubMed publication ID

3 December 2017

1593-1601

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Europe PubMed Central

PubMed publication ID

3 December 2017

Induction of apoptosis by chemotherapeutic drugs without generation of reactive oxygen species

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Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease

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Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells

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Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis

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Induction of cyclin-dependent kinase inhibitors and G(1) prolongation by the chemopreventive agent N-acetylcysteine

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Free radicals in biology: oxidative stress and the effects of ionizing radiation

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Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

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Application of the fluorescence resonance energy transfer method for studying the dynamics of caspase-3 activation during UV-induced apoptosis in living HeLa cells

1 reference

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p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.

1 reference

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The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

1 reference

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E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

1 reference

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E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

1 reference

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Transcriptional repression of the E2F-1 gene by interferon-alpha is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes

1 reference

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Increased expression of the transcription factor E2F1 during dopamine-evoked, caspase-3-mediated apoptosis in rat cortical neurons

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bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

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Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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Development of anticancer drugs targeting the MAP kinase pathway

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Vitamin E analog modulates UVB-induced signaling pathway activation and enhances cell survival

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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

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Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

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Cleavage of E2F-1-regulating proteins and activation of E2F-1 during CD95-induced death of thymocytes

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Antioxidant action via p53-mediated apoptosis

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Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase

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Effective elimination of lung metastases induced by tumor cells treated with hydrostatic pressure and N-acetyl-L-cysteine

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p53-Independent induction of apoptosis in human melanoma cells by a bcl-2/bcl-xL bispecific antisense oligonucleotide

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Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites

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10.1016/S0006-2952(03)00147-3

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Europe PubMed Central

PubMed publication ID

3 December 2017

release_qdfnnju6ffdxfnp5323hlmnikq

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https://api.fatcat.wiki/v0/release/qdfnnju6ffdxfnp5323hlmnikq

24 November 2022

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Europe PubMed Central

PubMed publication ID

3 December 2017

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