(Q44448848)

English

Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration

scientific article published on 19 May 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 December 2017

Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

prion protein family

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neurodegeneration

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based on heuristic

inferred from title

Ryuichiro Atarashi

1

object named as

Ryuichiro Atarashi

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Europe PubMed Central

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3 December 2017

author name string

Noriyuki Nishida

2

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Europe PubMed Central

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3 December 2017

Kazuto Shigematsu

3

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Europe PubMed Central

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3 December 2017

Shinji Goto

4

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Europe PubMed Central

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3 December 2017

Takahito Kondo

5

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Europe PubMed Central

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3 December 2017

Suehiro Sakaguchi

6

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Europe PubMed Central

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3 December 2017

Shigeru Katamine

7

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Europe PubMed Central

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3 December 2017

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publication date

19 May 2003

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Europe PubMed Central

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3 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

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3 December 2017

278

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Europe PubMed Central

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3 December 2017

31

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Europe PubMed Central

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3 December 2017

28944-28949

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Mice devoid of PrP are resistant to scrapie

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Prion Protein Biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Absence of the prion protein homologue Doppel causes male sterility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Doppel-induced cerebellar degeneration in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Two different neurodegenerative diseases caused by proteins with similar structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Truncated forms of the human prion protein in normal brain and in prion diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Peptide aggregation in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

A scrapie-like unfolding intermediate of the prion protein domain PrP(121-231) induced by acidic pH.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Copper stimulates endocytosis of the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Prion protein expression and superoxide dismutase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Electron paramagnetic resonance evidence for binding of Cu(2+) to the C-terminal domain of the murine prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Location and properties of metal-binding sites on the human prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

The PrP-like protein Doppel binds copper

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Prion protein protects human neurons against Bax-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Prions prevent neuronal cell-line death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Cellular prion protein transduces neuroprotective signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Brain copper content and cuproenzyme activity do not vary with prion protein expression level

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303655200

21 January 2018

Identifiers

10.1074/JBC.M303655200

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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