(Q44482330)

3 December 2017

title

MAPK and PI3K/AKT mediated YB-1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop (English)

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3 December 2017

6

Anja Bosserhoff

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3 December 2017

Tobias Sinnberg

1

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3 December 2017

Birgit Sauer

2

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3 December 2017

Per Holm

3

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3 December 2017

Barbara Spangler

4

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3 December 2017

Silke Kuphal

5

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3 December 2017

Birgit Schittek

7

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3 December 2017

publication date

1 April 2012

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3 December 2017

published in

Experimental Dermatology

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3 December 2017

volume

21

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3 December 2017

issue

4

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3 December 2017

page(s)

265-270

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The pleiotropic functions of the Y-box-binding protein, YB-1.

3 December 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01448.X

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Inhibition of protein synthesis by Y box-binding protein 1 blocks oncogenic cell transformation

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21 January 2018

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Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2.

21 January 2018

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Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition

21 January 2018

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Reduced proliferation and enhanced migration: two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1.

21 January 2018

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Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species

21 January 2018

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Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.

21 January 2018

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Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells

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Specifically regulated genes in malignant melanoma tissues identified by subtractive hybridization

21 January 2018

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The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance.

21 January 2018

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Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells

21 January 2018

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Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide

21 January 2018

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Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer

21 January 2018

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Structural and functional analysis of the human Y-box binding protein (YB-1) gene promoter

21 January 2018

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Identification of new genes associated with melanoma.

21 January 2018

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Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.

21 January 2018

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Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

21 January 2018

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The transcriptional induction of PIK3CA in tumor cells is dependent on the oncoprotein Y-box binding protein-1.

21 January 2018

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Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

21 January 2018

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21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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Nuclear localization of Y-box factor YB1 requires wild-type p53

21 January 2018

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Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression

21 January 2018

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Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells

21 January 2018

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21 January 2018

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Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

21 January 2018

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Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF.

21 January 2018

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Characterization of the 5'-untranslated region of YB-1 mRNA and autoregulation of translation by YB-1 protein

21 January 2018

1 reference

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YB-1 autoregulates translation of its own mRNA at or prior to the step of 40S ribosomal subunit joining

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01448.X

An essential role for protein synthesis in oncogenic cellular transformation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01448.X

Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01448.X

YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01448.X

10.1111/J.1600-0625.2012.01448.X

21 January 2018

Identifiers

DOI

1 reference

3 December 2017

1 reference