(Q44495144)

3 December 2017

title

The protein kinase pUL97 of human cytomegalovirus interacts with and phosphorylates the DNA polymerase processivity factor pUL44. (English)

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3 December 2017

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7

Thomas Stamminger

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3 December 2017

Manfred Marschall

1

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3 December 2017

Martina Freitag

2

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3 December 2017

Patricia Suchy

3

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3 December 2017

Daniel Romaker

4

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3 December 2017

Regina Kupfer

5

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3 December 2017

Miriam Hanke

6

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3 December 2017

language of work or name

English

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publication date

1 June 2003

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3 December 2017

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3 December 2017

volume

311

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3 December 2017

issue

1

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3 December 2017

page(s)

60-71

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The human cytomegalovirus genes and proteins required for DNA synthesis

3 December 2017

cites work

1 reference

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Relationship between autophosphorylation and phosphorylation of exogenous substrates by the human cytomegalovirus UL97 protein kinase

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7 January 2021

Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase. Importance of the P+5 position

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Alpha-, beta- and gammaherpesviruses encode a putative phosphotransferase

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A protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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A novel genetic system to detect protein-protein interactions

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Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity factor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94.

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Targeting of the gene product encoded by ORF UL56 of human cytomegalovirus into viral replication centers

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Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b

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Functional interaction between the pp71 protein of human cytomegalovirus and the PML-interacting protein human Daxx

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The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress

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7 January 2021

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

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Recombinant green fluorescent protein-expressing human cytomegalovirus as a tool for screening antiviral agents

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Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97.

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7 January 2021

Direct targeting of human cytomegalovirus protein kinase pUL97 by kinase inhibitors is a novel principle for antiviral therapy

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7 January 2021

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7 January 2021

Serine protein kinase associated with varicella-zoster virus ORF 47

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7 January 2021

Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) open reading frame 36 protein is a serine protein kinase

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7 January 2021

The UL13 gene of herpes simplex virus 1 encodes the functions for posttranslational processing associated with phosphorylation of the regulatory protein alpha 22

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7 January 2021

Viral and host-cell protein kinases: enticing antiviral targets and relevance of nucleoside, and viral thymidine, kinases

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7 January 2021

Open reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that contains a strong transcriptional activation domain

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7 January 2021

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

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7 January 2021

The human cytomegalovirus UL97 protein is phosphorylated and a component of virions

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7 January 2021

Functional interaction between pleiotropic transactivator pUL69 of human cytomegalovirus and the human homolog of yeast chromatin regulatory protein SPT6

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7 January 2021

Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation

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7 January 2021

Characterization of the human cytomegalovirus UL97 gene product as a virion-associated protein kinase

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7 January 2021

Human cytomegalovirus UL84 localizes to the cell nucleus via a nuclear localization signal and is a component of viral replication compartments

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7 January 2021

The UL112/113 gene products of human cytomegalovirus which colocalize with viral DNA in infected cell nuclei are related to efficient viral DNA replication

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7 January 2021

Indolocarbazoles exhibit strong antiviral activity against human cytomegalovirus and are potent inhibitors of the pUL97 protein kinase

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7 January 2021

The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10)

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7 January 2021

The Epstein-Barr virus thymidine kinase does not phosphorylate ganciclovir or acyclovir and demonstrates a narrow substrate specificity compared to the herpes simplex virus type 1 thymidine kinase

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7 January 2021

Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2.

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7 January 2021

A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency

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7 January 2021

Identification of new protein kinase-related genes in three herpesviruses, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus

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7 January 2021

Inhibition of Epstein-Barr virus replication by a benzimidazole L-riboside: novel antiviral mechanism of 5, 6-dichloro-2-(isopropylamino)-1-beta-L-ribofuranosyl-1H-benzimidazole

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7 January 2021

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Identifiers

DOI

1 reference

3 December 2017

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