(Q44495836)

English

An adenoviral vector containing an arg-gly-asp (RGD) motif in the fiber knob enhances protein product levels from transgenes refractory to expression

scientific article published in July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

An adenoviral vector containing an arg-gly-asp (RGD) motif in the fiber knob enhances protein product levels from transgenes refractory to expression (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

1 reference

based on heuristic

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author name string

Mel Campbell

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Shimian Qu

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Sam Wells

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Herlina Sugandha

4

1 reference

Europe PubMed Central

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3 December 2017

Roy A Jensen

5

1 reference

Europe PubMed Central

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3 December 2017

language of work or name

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inferred from title

publication date

1 July 2003

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Europe PubMed Central

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3 December 2017

Cancer Gene Therapy

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Europe PubMed Central

PubMed publication ID

3 December 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

559-570

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700599

0 references

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

1 reference

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HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

1 reference

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Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

1 reference

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21 January 2018

Cell receptors involved in adenovirus entry

1 reference

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21 January 2018

Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers

1 reference

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21 January 2018

Rational design of viral vectors based on rigorous analysis of capsid structures

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Determination of molecules regulating gene delivery using adenoviral vectors in ovarian carcinomas

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Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

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Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin

1 reference

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Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines

1 reference

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Modifications of the fiber in adenovirus vectors increase tropism for malignant glioma models

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Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX.

1 reference

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21 January 2018

Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions

1 reference

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Fiber shaft extension in combination with HI loop ligands augments infectivity for CAR-negative tumor targets but does not enhance hepatotropism in vivo

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In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus

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Effective gene transfer to human melanomas via integrin-targeted adenoviral vectors

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Fiber-mutant technique can augment gene transduction efficacy and anti-tumor effects against established murine melanoma by cytokine-gene therapy using adenovirus vectors

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Cancer susceptibility and the functions of BRCA1 and BRCA2

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BRCA1 transcriptionally regulates genes involved in breast tumorigenesis

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Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

1 reference

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21 January 2018

Growth retardation and tumour inhibition by BRCA1.

1 reference

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21 January 2018

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

1 reference

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21 January 2018

BRCA1-associated growth arrest is RB-dependent

1 reference

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21 January 2018

Distinct transcription start sites generate two forms of BRCA1 mRNA.

1 reference

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21 January 2018

Tumor suppressor p53 is required to modulate BRCA1 expression

1 reference

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21 January 2018

Regulation of BRCA1 by protein degradation

1 reference

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21 January 2018

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase

1 reference

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21 January 2018

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

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21 January 2018

A simplified system for generating recombinant adenoviruses

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21 January 2018

Establishment and characterization of human ovarian carcinoma cell lines

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21 January 2018

Visualizing the kinetics of tumor-cell clearance in living animals

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21 January 2018

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

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21 January 2018

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1 reference

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21 January 2018

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

1 reference

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21 January 2018

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

1 reference

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21 January 2018

BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

1 reference

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21 January 2018

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

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Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

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21 January 2018

Bioluminescent indicators in living mammals

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Using a tropism-modified adenoviral vector to circumvent inhibitory factors in ascites fluid

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21 January 2018

Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses

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21 January 2018

An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression

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21 January 2018

Efficient gene transfer by fiber-mutant adenoviral vectors containing RGD peptide

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21 January 2018

Insertion of an RGD motif into the HI loop of adenovirus fiber protein alters the distribution of transgene expression of the systemically administered vector

1 reference

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21 January 2018

Modification of a fiber protein in an adenovirus vector improves in vitro gene transfer efficiency to the mouse microglial cell line

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Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets

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An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches

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Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

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Transcriptional targeting for ovarian cancer gene therapy

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BRCA1 protein products: Antibody specificity…

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BRCA1 Facilitates Stress-induced Apoptosis in Breast and Ovarian Cancer Cell Lines

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An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

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Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

1 reference

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inferred from DOI database lookup

Location of BRCA1 in human breast and ovarian cancer cells

1 reference

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based on heuristic

inferred from DOI database lookup

Construction and characterization of recombinant adenoviruses expressing human BRCA1 or murine Brca1 genes

1 reference

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Structural determinants of BRCA1 translational regulation

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Identifiers

10.1038/SJ.CGT.7700599

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

ResearchGate publication ID

0 references

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