(Q44497218)

3 December 2017

title

A point mutation in influenza B neuraminidase confers resistance to peramivir and loss of slow binding (English)

1 reference

3 December 2017

Ellen Z Baum

1

1 reference

3 December 2017

Pamela C Wagaman

2

1 reference

3 December 2017

Linh Ly

3

1 reference

3 December 2017

Ignatius Turchi

4

1 reference

3 December 2017

Jianhua Le

5

1 reference

3 December 2017

Doris Bucher

6

1 reference

3 December 2017

Karen Bush

7

1 reference

3 December 2017

publication date

1 June 2003

1 reference

3 December 2017

1 reference

3 December 2017

volume

59

1 reference

3 December 2017

issue

1

1 reference

3 December 2017

page(s)

13-22

1 reference

BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Comparison of the anti-influenza virus activity of RWJ-270201 with those of oseltamivir and zanamivir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

In vitro selection and characterisation of influenza B/Beijing/1/87 isolates with altered susceptibility to zanamivir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Zanamivir susceptibility monitoring and characterization of influenza virus clinical isolates obtained during phase II clinical efficacy studies

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Three-dimensional structure of influenza A N9 neuraminidase and its complex with the inhibitor 2-deoxy 2,3-dehydro-N-acetyl neuraminic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Comparison of Structure and Sequence of Influenza B/Yamagata and B/Beijing Neuraminidases Shows a Conserved "Head" but Much Greater Variability in the "Stalk" and NB Protein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Isolation of immunogenic neuraminidases of human influenza viruses by a combination of genetic and biochemical procedures

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Influenza type B neuraminidase can replace the function of type A neuraminidase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Influenza virus neuraminidase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Evolutionary pattern of the hemagglutinin gene of influenza B viruses isolated in Japan: cocirculating lineages in the same epidemic season

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

GS4071 is a slow-binding inhibitor of influenza neuraminidase from both A and B strains

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Resistance of influenza viruses to neuraminidase inhibitors--a review.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en leads to instability of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Peramivir (BCX-1812, RWJ-270201): potential new therapy for influenza

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Characterization of an influenza A (H3N2) virus resistant to the cyclopentane neuraminidase inhibitor RWJ-270201.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Segment-specific and common nucleotide sequences in the noncoding regions of influenza B virus genome RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

Rational design of potent sialidase-based inhibitors of influenza virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2803%2900011-1

7 January 2021

10.1016/S0166-3542(03)00011-1

Identifiers

DOI

1 reference

3 December 2017

1 reference