(Q44499166)

English

Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines

scientific article published in July 2003

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scholarly article

1 reference

Europe PubMed Central

3 December 2017

Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines (English)

1 reference

Europe PubMed Central

3 December 2017

Hypericum perforatum

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0 references

2-(3,4-dihydroxyphenyl)-8-[(4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol

1 reference

1 reference

(+)-procyanidin B2

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author name string

Katarina Hostanska

1

1 reference

Europe PubMed Central

3 December 2017

Juergen Reichling

2

1 reference

Europe PubMed Central

3 December 2017

Silvia Bommer

3

1 reference

Europe PubMed Central

3 December 2017

Michel Weber

4

1 reference

Europe PubMed Central

3 December 2017

Reinhard Saller

5

1 reference

Europe PubMed Central

3 December 2017

language of work or name

0 references

publication date

1 July 2003

1 reference

Europe PubMed Central

3 December 2017

European Journal of Pharmaceutics and Biopharmaceutics

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Europe PubMed Central

3 December 2017

56

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Europe PubMed Central

3 December 2017

121-132

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Europe PubMed Central

3 December 2017

1

1 reference

Europe PubMed Central

3 December 2017

The killer and the executioner: how apoptosis controls malignancy.

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St John's wort for depression--an overview and meta-analysis of randomised clinical trials

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Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism

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A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy

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Studies on the inhibitory effects of quercetin on the growth of HL-60 leukemia cells

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Antioxidant activity and radioprotective effects against chromosomal damage induced in vivo by X-rays of flavan-3-ols (Procyanidins) from grape seeds (Vitis vinifera): comparative study versus other phenolic and organic compounds

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Topical application of St John's wort (Hypericum perforatum L.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells.

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Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.

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Hyperforin, possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L

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Adhyperforin: A Homologue of Hyperforin from Hypericum perforatum

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Peroxides as Constituents of Plants, Part 19: A C50-Hydroperoxide fromHypericum perforatum

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A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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Selective modulation of phosphatidylserine exposure on subpopulations of human peripheral blood lymphocytes by a plant lectin, Viscum album agglutinin (VAA)-I and its recombinant form (rVAA) in vitro

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Isolation, purity analysis and stability of hyperforin as a standard material from Hypericum perforatum L.

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Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers

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Measurement of hyperforin a constituent of St. John's wort in plasma by high-performance liquid chromatography

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Oral bioavailability of active principles from herbal products in humans. A study on Hypericum perforatum extracts using the soft gelatin capsule technology

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Anticarcinogenic effect of a polyphenolic fraction isolated from grape seeds in human prostate carcinoma DU145 cells: modulation of mitogenic signaling and cell-cycle regulators and induction of G1 arrest and apoptosis

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Down-modulation of P210bcr/abl induces apoptosis/differentiation in K562 leukemic blast cells

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Anti-cancer activities of hypericin in the dark

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Hyperforin as a possible antidepressant component of hypericum extracts

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Solubilized hypericin and pseudohypericin from Hypericum perforatum exert antidepressant activity in the forced swimming test

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Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

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Apoptosis without caspases: an inefficient molecular guillotine?

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Caspases: enemies within

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Identifiers

10.1016/S0939-6411(03)00046-8

1 reference

Europe PubMed Central

3 December 2017

1 reference

Europe PubMed Central

3 December 2017

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