(Q44499856)

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Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line

scientific article published in August 2003

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Europe PubMed Central

PubMed publication ID

3 December 2017

Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

Paul W Frohnert

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Mark S Stonecypher

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

publication date

1 August 2003

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Europe PubMed Central

PubMed publication ID

3 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

43

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

104-118

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Rat model of the human “Triton” tumor: direct genetic evidence for the myogenic differentiation capacity of schwannoma cells using the mutant neu gene as a cell lineage marker

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Synergistic regulation of Schwann cell proliferation by heregulin and forskolin

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Structural and functional aspects of the multiplicity of Neu differentiation factors

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Transformation of NIH 3T3 cells by overexpression of the normal coding sequence of the rat neu gene.

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Differential NF1, p16, and EGFR patterns by interphase cytogenetics (FISH) in malignant peripheral nerve sheath tumor (MPNST) and morphologically similar spindle cell neoplasms

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Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion

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Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

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Rb and TP53 pathway alterations in sporadic and NF1-related malignant peripheral nerve sheath tumors

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Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve

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Activation of neu by missense point mutation in the transmembrane domain in schwannomas induced in C3H/HeNCr mice by transplacental exposure to N-nitrosoethylurea

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Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration

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Studies on experimental malignant nerve sheath tumors maintained in tissue and organ culture systems II. Electron microscopy observations

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Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models

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Age- and dose-dependent transplacental carcinogenesis by N-nitrosoethylurea in Syrian golden hamsters

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Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors

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Teratogenic and carcinogenic effects in the offspring after single injection of ethylnitrosourea to pregnant rats.

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Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: Role of mesencephalic glia

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Biochemical and antiproliferative properties of 4-[Ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor

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A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

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ErbB transmembrane tyrosine kinase receptors are differentially expressed throughout the adult rat central nervous system

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Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins

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The neurofibromatoses: when less is more

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The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2.

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Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

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An anti-CD9 monoclonal antibody promotes adhesion and induces proliferation of Schwann cells in vitro

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Identification of heregulin, a specific activator of p185erbB2

1 reference

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Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

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Tumours of the nervous system induced in rats by the neonatal administration of n-ethyl-n-nitrosourea

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c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase

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Structure, expression and function of a schwannoma-derived growth factor

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Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts

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Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

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Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

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The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.

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Differential activation of NGF receptor and early response genes in neural crest-derived cells

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1 reference

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1 reference

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1 reference

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1 reference

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inferred from DOI database lookup

Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations.

1 reference

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based on heuristic

inferred from DOI database lookup

Schwann cell growth factors

1 reference

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Tyrosine kinase inhibitors. 14. Structure-activity relationships for methylamino-substituted derivatives of 4-[(3-bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase activity

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1 reference

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1 reference

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1 reference

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based on heuristic

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Clonal cell lines from the rat central nervous system.

1 reference

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inferred from DOI database lookup

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

1 reference

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Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro

1 reference

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

1 reference

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based on heuristic

inferred from DOI database lookup

Culture of cytogenetically abnormal schwann cells from benign and malignant NF1 tumors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Untangling the ErbB signalling network

1 reference

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Glial growth factor/neuregulin inhibits Schwann cell myelination and induces demyelination

1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/GLIA.10232

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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