(Q44499856)

English

Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line

scientific article published in August 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

0 references

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

Paul W Frohnert

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Mark S Stonecypher

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

publication date

1 August 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

43

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

104-118

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Rat model of the human “Triton” tumor: direct genetic evidence for the myogenic differentiation capacity of schwannoma cells using the mutant neu gene as a cell lineage marker

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NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors

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Synergistic regulation of Schwann cell proliferation by heregulin and forskolin

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Structural and functional aspects of the multiplicity of Neu differentiation factors

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21 January 2018

Transformation of NIH 3T3 cells by overexpression of the normal coding sequence of the rat neu gene.

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21 January 2018

Differential NF1, p16, and EGFR patterns by interphase cytogenetics (FISH) in malignant peripheral nerve sheath tumor (MPNST) and morphologically similar spindle cell neoplasms

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21 January 2018

Transplacental initiation of liver, lung, neurogenic, and connective tissue tumors by N-nitroso compounds in mice

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Expression of Kit in neurofibromin-deficient human Schwann cells: role in Schwann cell hyperplasia associated with type 1 neurofibromatosis.

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7 January 2021

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Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion

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Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

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The neu oncogene encodes an epidermal growth factor receptor-related protein

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Rb and TP53 pathway alterations in sporadic and NF1-related malignant peripheral nerve sheath tumors

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7 January 2021

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Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve

1 reference

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7 January 2021

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Glial growth factor-like activity in Schwann cell tumors.

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Activation of neu by missense point mutation in the transmembrane domain in schwannomas induced in C3H/HeNCr mice by transplacental exposure to N-nitrosoethylurea

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A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling

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Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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7 January 2021

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Studies on experimental malignant nerve sheath tumors maintained in tissue and organ culture systems II. Electron microscopy observations

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7 January 2021

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Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models

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7 January 2021

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Age- and dose-dependent transplacental carcinogenesis by N-nitrosoethylurea in Syrian golden hamsters

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7 January 2021

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Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

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Teratogenic and carcinogenic effects in the offspring after single injection of ethylnitrosourea to pregnant rats.

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7 January 2021

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Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: Role of mesencephalic glia

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7 January 2021

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Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

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A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

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ErbB transmembrane tyrosine kinase receptors are differentially expressed throughout the adult rat central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

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Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

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The neurofibromatoses: when less is more

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

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The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

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Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

1 reference

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7 January 2021

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An anti-CD9 monoclonal antibody promotes adhesion and induces proliferation of Schwann cells in vitro

1 reference

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7 January 2021

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Identification of heregulin, a specific activator of p185erbB2

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

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Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

1 reference

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7 January 2021

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Tumours of the nervous system induced in rats by the neonatal administration of n-ethyl-n-nitrosourea

1 reference

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7 January 2021

based on heuristic

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c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase

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7 January 2021

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Structure, expression and function of a schwannoma-derived growth factor

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Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts

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Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

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Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas

1 reference

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Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

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The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.

1 reference

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Differential activation of NGF receptor and early response genes in neural crest-derived cells

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Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

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Sorbitol accumulation and transmembrane efflux in osmotically stressed JS1 schwannoma cells.

1 reference

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based on heuristic

inferred from DOI database lookup

Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neu and its ligands: from an oncogene to neural factors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Schwann cell growth factors

1 reference

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7 January 2021

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Tyrosine kinase inhibitors. 14. Structure-activity relationships for methylamino-substituted derivatives of 4-[(3-bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase activity

1 reference

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The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Studies on experimental malignant nerve sheath tumors maintained in tissue and organ culture systems I. Light microscopy observations

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Role for the stem cell factor/KIT complex in Schwann cell neoplasia and mast cell proliferation associated with neurofibromatosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

A Mycobacterium leprae gene encoding a fibronectin binding protein is used for efficient invasion of epithelial cells and Schwann cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Sensory and motor neuron-derived factor is a transmembrane heregulin that is expressed on the plasma membrane with the active domain exposed to the extracellular environment

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Clonal cell lines from the rat central nervous system.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic significance of ERBB3 overexpression in oral squamous cell carcinoma

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Culture of cytogenetically abnormal schwann cells from benign and malignant NF1 tumors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Untangling the ErbB signalling network

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Glial growth factor/neuregulin inhibits Schwann cell myelination and induces demyelination

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10232

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/GLIA.10232

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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