(Q44508752)

3 December 2017

title

CDKN2A point mutations D153spl(c.457G>T) and IVS2+1G>T result in aberrant splice products affecting both p16INK4a and p14ARF. (English)

1 reference

3 December 2017

Joni L Rutter

1

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Jeffery Struewing

object named as

Jeffery P Struewing

series ordinal

5

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Michael R Dávila

series ordinal

3

object named as

Michael R Dávila

1 reference

3 December 2017

4

Margaret A Tucker

1 reference

3 December 2017

2

Alisa M Goldstein

1 reference

3 December 2017

language of work or name

English

0 references

publication date

1 July 2003

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3 December 2017

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3 December 2017

volume

22

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3 December 2017

issue

28

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3 December 2017

page(s)

4444-4448

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Genotype-Phenotype Relationships in U.S. Melanoma-Prone Families With CDKN2A and CDK4 Mutations

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Genetic epidemiology of cutaneous melanoma: a global perspective

21 January 2018

1 reference

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Splicing into senescence: the curious case of p16 and p19ARF.

21 January 2018

1 reference

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A deep intronic mutation in CDKN2A is associated with disease in a subset of melanoma pedigrees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Germline p16 mutations in familial melanoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

A cell cycle regulator potentially involved in genesis of many tumor types

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Counseling and DNA testing for individuals perceived to be genetically predisposed to melanoma: A consensus statement of the Melanoma Genetics Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: causes and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

UTRdb: a specialized database of 5' and 3' untranslated regions of eukaryotic mRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Differential expression of p16INK4a and p16beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

p16(MTS-1/CDKN2/INK4a) in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

CDKN2A germline splicing mutation affecting both p16ink4 and p14arf RNA processing in a melanoma/neurofibroma kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206564

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1206564

1 reference

3 December 2017

1 reference