(Q44526097)

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Down-regulation of glutathione and Bcl-2 synthesis in mouse B16 melanoma cells avoids their survival during interaction with the vascular endothelium.

scientific article published on 24 July 2003

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Europe PubMed Central

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6 November 2019

Down-regulation of glutathione and Bcl-2 synthesis in mouse B16 melanoma cells avoids their survival during interaction with the vascular endothelium (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12881529%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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Julian Carretero

3

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6 November 2019

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6 November 2019

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Angel Ortega

1

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6 November 2019

Paula Ferrer

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6 November 2019

Miguel Asensi

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6 November 2019

José A Pellicer

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6 November 2019

José M Estrela

7

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6 November 2019

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24 July 2003

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6 November 2019

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9

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Journal of Biological Chemistry

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6 November 2019

278

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6 November 2019

41

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6 November 2019

39591-39599

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6 November 2019

Biomechanical interactions of cancer cells with the microvasculature during hematogenous metastasis

1 reference

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Lethal deformation of cancer cells in the microcirculation: A potential rate regulator of hematogenous metastasis

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21 January 2018

Tumoricidal activity of endothelial cells. Inhibition of endothelial nitric oxide production abrogates tumor cytotoxicity induced by hepatic sinusoidal endothelium in response to B16 melanoma adhesion in vitro

1 reference

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21 January 2018

Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature.

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21 January 2018

gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver

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Apoptosis in cancer

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Anti-cell death activity promotes pulmonary metastasis of melanoma cells

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21 January 2018

Fas and Fas ligand interactions suppress melanoma lung metastasis

1 reference

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21 January 2018

BCL-2 proteins: regulators of the mitochondrial apoptotic program

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21 January 2018

Apoptosis and tumourigenesis

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21 January 2018

Mitochondrial control of cell death

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21 January 2018

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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21 January 2018

Development of resistance to glutathione depletion-induced cell death in CC531 colon carcinoma cells: association with increased expression of bcl-2.

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21 January 2018

Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester

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21 January 2018

Glutamine potentiates TNF-alpha-induced tumor cytotoxicity

1 reference

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21 January 2018

Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease.

1 reference

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21 January 2018

Tumor cytotoxicity by endothelial cells. Impairment of the mitochondrial system for glutathione uptake in mouse B16 melanoma cells that survive after in vitro interaction with the hepatic sinusoidal endothelium.

1 reference

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21 January 2018

An endotoxin-induced serum factor that causes necrosis of tumors

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Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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21 January 2018

The machinery of programmed cell death.

1 reference

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21 January 2018

Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice

1 reference

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21 January 2018

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth

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21 January 2018

Antisense therapy for cancer--the time of truth

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21 January 2018

Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines

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21 January 2018

BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity

1 reference

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21 January 2018

Transfer of anti-TFAR19 monoclonal antibody into HeLa cells by in situ electroporation can inhibit the apoptosis

1 reference

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21 January 2018

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

1 reference

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21 January 2018

Inhibition of target cell mitochondrial electron transfer by tumor necrosis factor

1 reference

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21 January 2018

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity

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21 January 2018

Role of Bcl-2 family of proteins in malignancy

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21 January 2018

Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells

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21 January 2018

Immunohistochemical markers of melanocytic tumors

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21 January 2018

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

1 reference

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21 January 2018

Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells.

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21 January 2018

Bcl-2 expression causes redistribution of glutathione to the nucleus

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Redox regulation of transcriptional activators

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Thioltransferase (glutaredoxin) is detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro

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Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

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Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides

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21 January 2018

Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines

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Increased resting energy expenditure and weight loss are related to a systemic inflammatory response in lung cancer patients

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Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells

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Elimination of Ehrlich tumours by ATP-induced growth inhibition, glutathione depletion and X-rays

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Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

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Growth-associated changes in glutathione content correlate with liver metastatic activity of B16 melanoma cells

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Changes in mitochondrial membrane potential during staurosporine-induced apoptosis in Jurkat cells

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Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

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bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

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Identifiers

10.1074/JBC.M303753200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12881529%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12881529%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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