(Q44548846)

4 December 2017

title

Suppressor of cytokine signaling 1 regulates an endogenous inhibitor of a mast cell protease (English)

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4 December 2017

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Robert Rottapel

4

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author name string

Subburaj Ilangumaran

series ordinal

1

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4 December 2017

Dina Finan

series ordinal

2

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4 December 2017

Jason Raine

series ordinal

3

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4 December 2017

language of work or name

English

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publication date

12 August 2003

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Journal of Biological Chemistry

4 December 2017

published in

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4 December 2017

volume

278

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4 December 2017

issue

43

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4 December 2017

page(s)

41871-41880

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Cytokine receptor signal transduction and the control of hematopoietic cell development

4 December 2017

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Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

21 January 2018

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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

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Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

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Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

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Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

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21 January 2018

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Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse

21 January 2018

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The tryptase, mouse mast cell protease 7, exhibits anticoagulant activity in vivo and in vitro due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma

21 January 2018

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21 January 2018

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21 January 2018

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Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension

21 January 2018

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Tryptase 4, a new member of the chromosome 17 family of mouse serine proteases.

21 January 2018

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Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism

21 January 2018

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Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation

21 January 2018

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Roles of mast cells and basophils in innate and acquired immunity

21 January 2018

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Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1.

21 January 2018

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Mast cell tryptases and airway remodeling

21 January 2018

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Regulation and function of mast cell proteases in inflammation

21 January 2018

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Mechanism for Activation of Mouse Mast Cell Tryptase: Dependence on Heparin and Acidic pH for Formation of Active Tetramers of Mouse Mast Cell Protease 6†

21 January 2018

1 reference

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Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood

21 January 2018

1 reference

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Role of Janus kinase 3 in mast cell-mediated innate immunity against gram-negative bacteria

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M308382200

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4 December 2017

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