(Q44551574)

4 December 2017

title

Isoform switching of Cdc6 contributes to developmental cell cycle remodeling (English)

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4 December 2017

Nadia Tikhmyanova

1

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4 December 2017

Thomas R Coleman

series ordinal

2

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4 December 2017

language of work or name

English

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publication date

1 August 2003

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4 December 2017

published in

Developmental Biology

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4 December 2017

volume

260

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4 December 2017

issue

2

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4 December 2017

page(s)

362-375

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DNA replication in eukaryotic cells

4 December 2017

cites work

1 reference

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Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus

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Xenopus Cdc6 performs separate functions in initiating DNA replication

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Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication

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Site-specific initiation of DNA replication in Xenopus egg extract requires nuclear structure

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A role for cyclin E/Cdk2 in the timing of the midblastula transition in Xenopus embryos

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Mutation of cyclin/cdk phosphorylation sites in HsCdc6 disrupts a late step in initiation of DNA replication in human cells

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The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells

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Identification of a developmental timer regulating the stability of embryonic cyclin A and a new somatic A-type cyclin at gastrulation

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A developmental timer regulates degradation of cyclin E1 at the midblastula transition during Xenopus embryogenesis

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Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2

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Transition in specification of embryonic metazoan DNA replication origins

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sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast

7 January 2021

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Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

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A maternal form of the phosphatase Cdc25A regulates early embryonic cell cycles in Xenopus laevis

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Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle

7 January 2021

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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

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Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1

7 January 2021

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Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

7 January 2021

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7 January 2021

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7 January 2021

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Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogaster

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Developmental regulation of MCM replication factors in Xenopus laevis

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Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin

7 January 2021

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Xenopus Cdc6 confers sperm binding competence to oocytes without inducing their maturation

7 January 2021

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Regulation of replicon size in Xenopus egg extracts.

7 January 2021

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Origin-specific initiation of mammalian nuclear DNA replication in a Xenopus cell-free system

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0012-1606(03)00253-7

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4 December 2017

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