(Q44555704)

English

Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes

scientific article published in September 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 December 2017

Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Tamara Vanhaecke

3

object named as

Tamara Vanhaecke

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

7

object named as

Vera Rogiers

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Christiane Guguen-Guillouzo

6

object named as

Christiane Guguen-Guillouzo

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

author name string

Peggy Papeleu

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Pascal Loyer

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Greetje Elaut

4

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Albert Geerts

5

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

publication date

1 September 2003

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Journal of Hepatology

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Europe PubMed Central

PubMed publication ID

4 December 2017

39

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

3

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Europe PubMed Central

PubMed publication ID

4 December 2017

374-382

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Histone deacetylase as a therapeutic target

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

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Neuronal Differentiation of Neuro 2a Cells by Inhibitors of Cell Cycle Progression, Trichostatin A and Butyrolactone I

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Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell lines.

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The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells

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Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells

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A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture

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Effect of the histone deacetylase inhibitor trichostatin A on the responsiveness of rat hepatocytes to dioxin

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Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes

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Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

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Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes

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Liver regeneration

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Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1

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The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

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Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

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Western blotting of histones from acid-urea-Triton- and sodium dodecyl sulfate-polyacrylamide gels

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Interaction between the cell-cycle-control proteins p34cdc2 and p9CKShs2. Evidence for two cooperative binding domains in p9CKShs2

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Biochemical characteristics of caspases-3, -6, -7, and -8

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Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

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Progression through G1 and S phases of adult rat hepatocytes.

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7 January 2021

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PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

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Hepatocyte proliferative activity in human liver cirrhosis

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Effects of cell density and trichostatin A on the expression of HDAC1 and p57Kip2 in Hep 3B cells

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Genes modulated by histone acetylation as new effectors of butyrate activity

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Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression

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Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells

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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression

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Identifiers

10.1016/S0168-8278(03)00288-5

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

release_zvqabehnzfc3bjt3s2ifh3iquy

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24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

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4 December 2017

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