(Q44559480)

4 December 2017

title

Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons (English)

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4 December 2017

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C G Besirli

1

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4 December 2017

T L Deckwerth

2

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4 December 2017

R J Crowder

3

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4 December 2017

R S Freeman

4

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4 December 2017

E M Johnson

5

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4 December 2017

publication date

1 September 2003

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Cell Death & Differentiation

4 December 2017

published in

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4 December 2017

volume

10

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4 December 2017

issue

9

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4 December 2017

page(s)

1045-1058

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401259

4 December 2017

exact match

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cites work

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Cerebellar degeneration caused by high-dose cytosine arabinoside: a clinicopathological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Filamentous degeneration of neurons. A possible feature of cytosine arabinoside neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Central nervous system toxicity of high-dose systemic cytosine arabinoside

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

The mechanism of Ara-C-induced apoptosis of differentiating cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Cell birth, cell death, cell diversity and DNA breaks: how do they all fit together?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Rearranging views on neurogenesis: neuronal death in the absence of DNA end-joining proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

BID: a novel BH3 domain-only death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Bid regulation of neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

BAX is required for neuronal death after trophic factor deprivation and during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Analysis of the effects of the antiserum to the nerve growth factor in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Analysis of a novel mechanism of neuronal toxicity produced by an apolipoprotein E-derived peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Cytosine arabinoside induces apoptosis in cerebellar neurons in culture.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

p53 protein in sympathetic neurons: cytoplasmic localization and no apparent function in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Techniques in the tissue culture of rat sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401259

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401259

1 reference

4 December 2017

1 reference