(Q46672215)

24 December 2017

title

Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants (English)

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24 December 2017

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Zarir E Karanjawala

1

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24 December 2017

Niamh Murphy

2

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24 December 2017

David R Hinton

3

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24 December 2017

Chih Lin Hsieh

4

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24 December 2017

Michael R Lieber

5

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24 December 2017

language of work or name

English

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publication date

1 March 2002

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24 December 2017

published in

Current Biology

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24 December 2017

volume

12

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24 December 2017

page(s)

397-402

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24 December 2017

issue

5

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24 December 2017

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

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7 January 2021

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Hydroperoxide metabolism in mammalian organs

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Mitochondrial free radical generation, oxidative stress, and aging

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Quality control by DNA repair

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Warner-Lambert/Parke-Davis Award Lecture. Pathological and physiological double-strand breaks: roles in cancer, aging, and the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Chromosomal stability and the DNA double-stranded break connection

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Oxidative stress mediates impairment of muscle function in transgenic mice with elevated level of wild-type Cu/Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice

1 reference

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7 January 2021

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Deletion of Ku86 causes early onset of senescence in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Analysis of ku80-mutant mice and cells with deficient levels of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Apoptosis in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900684-X

7 January 2021

10.1016/S0960-9822(02)00684-X

Identifiers

DOI

1 reference

24 December 2017

PubMed ID

11882291

1 reference

24 December 2017