(Q44563626)

4 December 2017

title

Bone-targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues (English)

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4 December 2017

Raji Sundaramoorthi

1

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4 December 2017

William C Shakespeare

2

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4 December 2017

Terence P Keenan

3

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4 December 2017

Chester A Metcalf

4

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4 December 2017

Yihan Wang

5

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4 December 2017

Ukti Mani

6

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4 December 2017

Merry Taylor

7

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4 December 2017

Shuangying Liu

8

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4 December 2017

Regine S Bohacek

9

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4 December 2017

Surinder S Narula

10

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4 December 2017

David C Dalgarno

11

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4 December 2017

Marie Rose van Schravandijk

12

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4 December 2017

Sheila M Violette

13

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4 December 2017

Shuenn Liou

14

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4 December 2017

Susan Adams

15

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4 December 2017

Mary K Ram

16

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4 December 2017

Jeffrey A Keats

17

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4 December 2017

Manfred Weigle

18

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4 December 2017

Tomi K Sawyer

19

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4 December 2017

Manfred Weigele

20

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4 December 2017

language of work or name

English

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publication date

1 September 2003

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Bioorganic & Medicinal Chemistry Letters

4 December 2017

published in

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4 December 2017

volume

13

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4 December 2017

issue

18

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4 December 2017

page(s)

3063-3066

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Therapeutic approaches to bone diseases

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

The osteoblast: a sophisticated fibroblast under central surveillance

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https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Bone resorption by osteoclasts

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https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Decreased c-Src expression enhances osteoblast differentiation and bone formation

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https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

SRC homology-2 inhibitors: peptidomimetic and nonpeptide

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Targeting protein kinases for bone disease: discovery and development of Src inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

Bisphosphonates as a foundation of drug delivery to bone

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900647-4

7 January 2021

10.1016/S0960-894X(03)00647-4

Identifiers

DOI

1 reference

4 December 2017

1 reference