(Q44578015)

4 December 2017

Essential role of histidine 84 in elongation factor Tu for the chemical step of GTP hydrolysis on the ribosome (English)

1 reference

4 December 2017

3

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4 December 2017

Tina Daviter

1

1 reference

PubMed ID

12963376

4 December 2017

Hans-Joachim Wieden

series ordinal

2

1 reference

PubMed ID

12963376

4 December 2017

language of work or name

English

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publication date

1 September 2003

1 reference

Journal of Molecular Biology

4 December 2017

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4 December 2017

332

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4 December 2017

3

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4 December 2017

689-699

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

4 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Crystal structure of active elongation factor Tu reveals major domain rearrangements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Why have mutagenesis studies not located the general base in ras p21.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Mechanistic analysis of the observed linear free energy relationships in p21ras and related systems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

The GTPase superfamily: conserved structure and molecular mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Conformational change of elongation factor Tu (EF-Tu) induced by antibiotic binding. Crystal structure of the complex between EF-Tu.GDP and aurodox

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Mechanism of action of kirromycin-like antibiotics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Mutagenesis of three residues, isoleucine-60, threonine-61, and aspartic acid-80, implicated in the GTPase activity of Escherichia coli elongation factor Tu

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Substitution of histidine-84 and the GTPase mechanism of elongation factor Tu.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Relevance of histidine-84 in the elongation factor Tu GTPase activity and in poly(Phe) synthesis: its substitution by glutamine and alanine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Site-directed mutagenesis of Thermus thermophilus elongation factor Tu. Replacement of His85, Asp81 and Arg300.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

The importance of structural transitions of the switch II region for the functions of elongation factor Tu on the ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Initial binding of the elongation factor Tu.GTP.aminoacyl-tRNA complex preceding codon recognition on the ribosome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Effect of ribosome binding and translocation on the anticodon of tRNAPhe as studied by wybutine fluorescence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

EFTu provides an internal kinetic standard for translational accuracy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Kinetic mechanism of elongation factor Ts-catalyzed nucleotide exchange in elongation factor Tu.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Partition analysis and concept of net rate constants as tools in enzyme kinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Dynamics and morphology of the in vitro polymeric form of elongation factor Tu from Escherichia coli.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Elongation factor Tu, a GTPase triggered by codon recognition on the ribosome: mechanism and GTP consumption

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Site-directed mutagenesis of Arg58 and Asp86 of elongation factor Tu from Escherichia coli: effects on the GTPase reaction and aminoacyl-tRNA binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Mutational analysis of Escherichia coli elongation factor Tu in search of a role for the N-terminal region.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Contribution of Arg288 of Escherichia coli elongation factor Tu to translational functionality.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Visualization of elongation factor Tu on the Escherichia coli ribosome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

GTPase activation of elongation factors Tu and G on the ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Mechanism of elongation factor (EF)-Ts-catalyzed nucleotide exchange in EF-Tu. Contribution of contacts at the guanine base

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

The identification and analysis of nucleotides bound to the elongation factor Tu from Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

Kinetic properties of Escherichia coli ribosomes with altered forms of S12

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900947-1

10.1016/S0022-2836(03)00947-1

7 January 2021

Identifiers

DOI

1 reference

4 December 2017

1 reference

PubMed ID

12963376