(Q44579065)

English

Increased formic acid excretion and the development of kidney toxicity in rats following chronic dosing with trichloroethanol, a major metabolite of trichloroethylene

scientific article published in September 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Increased formic acid excretion and the development of kidney toxicity in rats following chronic dosing with trichloroethanol, a major metabolite of trichloroethylene (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

author name string

Trevor Green

1

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Europe PubMed Central

PubMed publication ID

4 December 2017

Jacky Dow

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

John Foster

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

language of work or name

0 references

publication date

1 September 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

number of pages

11

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PubMed publication ID

4 December 2017

191

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Europe PubMed Central

PubMed publication ID

4 December 2017

2-3

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Europe PubMed Central

PubMed publication ID

4 December 2017

109-119

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure

1 reference

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Renal toxicity and carcinogenicity of trichloroethylene: key results, mechanisms, and controversies

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Preexistence of chronic tubular damage in cases of renal cell cancer after long and high exposure to trichloroethylene.

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Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethene

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Glutathione transferase alpha as a marker for tubular damage after trichloroethylene exposure.

1 reference

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Trichloroethylene induced vitamin B(12) and folate deficiency leads to increased formic acid excretion in the rat.

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Inhibitors of cytochrome c oxidase

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Acid-labile adducts to protein can be used as indicators of the cysteine S-conjugate pathway of trichloroethene metabolism.

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Renal activation of trichloroethene and S-(1,2-dichlorovinyl)-L-cysteine and cell proliferative responses in the kidneys of F344 rats and B6C3F1 mice.

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Inhalation carcinogenicity of trichloroethylene in mice and rats.

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Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway.

1 reference

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Potential role of alpha-2 mu-globulin, protein droplet accumulation, and cell replication in the renal carcinogenicity of rats exposed to trichloroethylene, perchloroethylene, and pentachloroethane

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Species differences in response to trichloroethylene. II. Biotransformation in rats and mice.

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The role of glutathione conjugation in the development of kidney tumours in rats exposed to trichloroethylene.

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Formic acid excretion in rats exposed to trichloroethylene: a possible explanation for renal toxicity in long-term studies.

1 reference

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Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species.

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Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes

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Farmers' exposure to formic acid vapour in silage making

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Effect of renal formic acid excretion on urinary calcium and ammonia concentrations

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Methanol and Formic Acid Toxicity: Biochemical Mechanisms

1 reference

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Kinetics and renal effects of formic acid in occupationally exposed farmers

1 reference

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Long-term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice.

1 reference

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The effect of formate on cytochrome aa3 and on electron transport in the intact respiratory chain

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Chloride transport in the mammalian proximal tubule

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Image analysis of bromodeoxyuridine (BrdU) staining for measurement of S-phase in rat and mouse liver

1 reference

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The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats.

1 reference

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7 January 2021

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Renal effects of metabolic acidosis in the normal rat

1 reference

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Renal cell cancer correlated with occupational exposure to trichloroethene

1 reference

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Biochemical and toxicological effects of single and repeated exposures to polyacetal thermodegradation products.

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Identifiers

10.1016/S0300-483X(03)00206-3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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