(Q33942236)

30 July 2017

1 reference

title

Renal toxicity and carcinogenicity of trichloroethylene: key results, mechanisms, and controversies (English)

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30 July 2017

0 references

T Brüning

1

1 reference

PubMed ID

10852497

30 July 2017

H M Bolt

series ordinal

2

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PubMed ID

10852497

30 July 2017

language of work or name

English

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publication date

1 May 2000

1 reference

Critical Reviews in Toxicology

30 July 2017

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30 July 2017

30

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30 July 2017

3

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30 July 2017

253-285

1 reference

Dose-dependent binding of trichloroethylene to hepatic DNA and protein at low doses in mice.

30 July 2017

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Increased frequency of micronucleated kidney cells in rats exposed to halogenated anaesthetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Metabolism of trichloroethene--in vivo and in vitro evidence for activation by glutathione conjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Use of kinetic and mechanistic data in species extrapolation of bioactivation: cytochrome P-450 dependent trichloroethylene metabolism at occupationally relevant concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Oxidation of trichloroethylene by liver microsomal cytochrome P-450: evidence for chlorine migration in a transition state not involving trichloroethylene oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Bioactivation of xenobiotics by formation of toxic glutathione conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

The role of glutathione conjugation in the development of kidney tumours in rats exposed to trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

A role for c-myc in chemically induced renal-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Formic acid excretion in rats exposed to trichloroethylene: a possible explanation for renal toxicity in long-term studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Inhalation pharmacokinetics based on gas uptake studies. II. Pharmacokinetics of acetone in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Effect of hexachloro-1,3-butadiene on renal carcinogenesis in male rats pretreated with N-ethyl-N-hydroxyethylnitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Cancer in relation to occupational exposure to trichloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Organic solvents and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Assessment of the health effects of trichloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

A critical review of epidemiology studies of trichloroethylene and perchloroethylene and risk of renal-cell cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Renal cell cancer correlated with occupational exposure to trichloroethene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

International renal-cell cancer study. IV. Occupation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: extended follow up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Preexistence of chronic tubular damage in cases of renal cell cancer after long and high exposure to trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Characterization of proteinuria in primary glomerulonephritides. SDS-PAGE patterns: clinical significance and prognostic value of low molecular weight ("tubular") proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Pathological excretion patterns of urinary proteins in renal cell cancer patients exposed to trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Glutathione transferase alpha as a marker for tubular damage after trichloroethylene exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Cytochrome P450 4A and 2E1 expression in human kidney microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Identification of the von Hippel-Lindau disease tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mutations of the VHL tumour suppressor gene in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Renal cell carcinomas in trichloroethene (TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Carcinogenicity of trichloroethylene: fact or artifact?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Carcinogenicity studies on halogenated hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

The von Hippel-Lindau tumour suppressor protein: new perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Von Hippel-Lindau (VHL) disease with pheochromocytoma in the Black Forest region of Germany: evidence for a founder effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mutation and cancer: statistical study of retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

S-(1,2-dichlorovinyl)-L-cysteine-induced dedifferentiation and p53 gene mutations in LLC-PK1 cells: a comparative investigation with S-(2-chloroethyl)cysteine, potassium bromate, cis-platinum and styrene oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

von Hippel-Lindau gene mutations in N-nitrosodimethylamine-induced rat renal epithelial tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Combining physiologically based pharmacokinetic modeling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Changes in the classification of carcinogenic chemicals in the work area. Section III of the German List of MAK and BAT Values.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

An association between mutagenicity of the Ara test of Salmonella typhimurium and carcinogenicity in rodents for 16 halogenated aliphatic hydrocarbons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mutagenicity of inhalation anaesthetics: trichloroethylene, divinyl ether, nitrous oxide and cyclopropane

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Activities of chlorinated ethane and ethylene compounds in the Salmonella/rat microsome mutagenesis and rat hepatocyte/DNA repair assays under vapor phase exposure conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Conditions affecting the mutagenicity of trichloroethylene in Salmonella

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mutagenicity of trichloroethylene, trichloroethanol and chloral hydrate in Aspergillus nidulans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

In vivo and in vitro mutagenicity studies of a possible carcinogen, trichloroethylene, and its two stabilizers, epichlorohydrin and 1,2-epoxybutane

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: evaluations of 108 chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Transforming activities of trichloroethylene and proposed industrial alternatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Metabolism of [14C]trichloroethylene to 14CO2 and interaction of a metabolite with liver DNA in rats and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Mortality of aircraft manufacturing workers in southern California

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Spermatid micronucleus analyses of trichloroethylene and chloral hydrate effects in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Inhalation studies of the genotoxicity of trichloroethylene to rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Trichloroethylene vapours do not produce dominant lethal mutations in male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Inhalation carcinogenicity of trichloroethylene in mice and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Long-term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440091159202

10.1080/10408440091159202

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10852497