(Q44582070)

4 December 2017

title

Pharmacokinetics of clozapine and its metabolites in hippocampal HT22 cells (English)

1 reference

4 December 2017

1 reference

5

Helmut Remschmidt

1 reference

4 December 2017

Philip Heiser

1

1 reference

4 December 2017

M Schüler-Springorum

2

1 reference

4 December 2017

Eva Schulte

3

1 reference

4 December 2017

Christiane Hausmann

4

1 reference

4 December 2017

Jürgen-Christian Krieg

6

1 reference

4 December 2017

Helmut Vedder

7

1 reference

4 December 2017

language of work or name

English

0 references

publication date

1 August 2003

1 reference

European Journal of Pharmacology

4 December 2017

published in

1 reference

4 December 2017

volume

476

1 reference

4 December 2017

issue

3

1 reference

4 December 2017

page(s)

167-172

1 reference

Clozapine pharmacokinetics and pharmacodynamics studied with Cyp1A2-null mice

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Cytochrome P4502D6 genotype does not determine response to clozapine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Messenger RNA of steroid 21-hydroxylase (CYP21) is expressed in the human hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Evidence from a population pharmacokinetics analysis for a major effect of CYP1A2 activity on inter- and intraindividual variations of clozapine clearance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Serotonin2 receptors and the serotonin transporter in the schizophrenic brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Long-term therapeutic drug monitoring of clozapine and metabolites in psychiatric in- and outpatients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Gating of information flow within the limbic system and the pathophysiology of schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Multiple-dose pharmacokinetics of clozapine in patients with chronic schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Absence of interaction between erythromycin and a single dose of clozapine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Uptake of clozapine into HL-60 promyelocytic leukaemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of cytochrome P450 1A1, the aryl hydrocarbon receptor, and the aryl hydrocarbon receptor nuclear translocator in rat brain and pituitary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Schizophrenia and cognitive function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Induction and expression of long- and short-term neurosecretory potentiation in a neural cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Distribution and induction of cytochrome P450 1A1 and 1A2 in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Changes in the serotonin transporter in the hippocampus of subjects with schizophrenia identified using [3H]paroxetine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Determination of clozapine in serum by radioreceptor assay versus high-performance liquid chromatography: possible detection of hydroxy-metabolites.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C-->A polymorphism in intron 1 of the CYP1A2 gene: effect of grapefruit juice and low-dose fluvoxamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Drug metabolism and atypical antipsychotics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Serum concentrations of clozapine and N-desmethylclozapine are unaffected by the potent CYP3A4 inhibitor itraconazole

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Differential effects of neuroleptic agents on hepatic cytochrome P-450 isozymes in the male rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Expression and distribution of CYP2C enzymes in rat basal ganglia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

A proposed pathological model in the hippocampus of subjects with schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Determination of clozapine and its major metabolites in serum samples of adolescent schizophrenic patients by high-performance liquid chromatography. Data from a prospective clinical trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Blood biogenic amines during clozapine treatment of early-onset schizophrenia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Expression of CYP19 (aromatase) mRNA in different areas of the human brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Cytochrome P4502E (CYP2E) in brain: constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Regulation of glucocorticoid receptor-mRNA in human blood cells by amitriptyline and dexamethasone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Sex- and age-specific differences in human brain CYP11A1 mRNA expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

Effects of desmethylclozapine on Fos protein expression in the forebrain: in vivo biological activity of the clozapine metabolite

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902176-9

10.1016/S0014-2999(03)02176-9

7 January 2021

Identifiers

DOI

1 reference

4 December 2017

1 reference