(Q44600629)

English

Okadaic acid, an inhibitor of protein phosphatase 1 and 2A, induces premature separation of sister chromatids during meiosis I and aneuploidy in mouse oocytes in vitro

scientific article published on January 1, 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Okadaic acid, an inhibitor of protein phosphatase 1 and 2A, induces premature separation of sister chromatids during meiosis I and aneuploidy in mouse oocytes in vitro (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1 reference

10.1023/A:1024909119593

https://api.crossref.org/works/10.1023/A:1024909119593

15 March 2024

author name string

Colette Hilliard

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

John B. Mailhes

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14516070

15 March 2024

John W. Fuseler

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14516070

15 March 2024

Steve N. London

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14516070

15 March 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14516070

15 March 2024

publication date

1 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Chromosome Research

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

619-631

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

https://scigraph.springernature.com/pub.10.1023/a:1024909119593

0 references

Deadly encounter: ubiquitin meets apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frontier questions about sister chromatid separation in anaphase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemically-induced aneuploidy in mammalian oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of cAMP-dependent protein kinase and protein phosphorylation in regulation of mouse oocyte maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splitting the chromosome: cutting the ties that bind sister chromatids

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mitosis by okadaic acid: possible involvement of a protein phosphatase 2A in the transition from metaphase to anaphase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of non-disjunction in human female meiosis: the co-existence of two modes of malsegregation evidenced by the karyotyping of 1397 in-vitro unfertilized oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure and regulation of protein phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and functions of the 20S and 26S proteasomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphatases control MAP kinase activation and microtubule organization during rat oocyte maturation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphatases are involved in the in vivo activation of histone H1 kinase in mouse oocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MG-132, an inhibitor of proteasomes and calpains, induced inhibition of oocyte maturation and aneuploidy in mouse oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sister-chromatid cohesion in mitosis and meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinases in meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of protein phosphatases in mouse oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular basis of sister-chromatid cohesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accessory protein regulation of microtubule dynamics throughout the cell cycle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid: a new probe for the study of cellular regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secured cutting: controlling separase at the metaphase to anaphase transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maternal age, paternal age, and human chromosome abnormality: nature, magnitude, etiology, and mechanisms of effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein phosphatase inhibitor okadaic acid inhibits exit from metaphase II in parthenogenetically activated pig oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of c-mos proto-oncogene product in the regulation of mouse oocyte maturation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyses of mRNA expression patterns of cohesin subunits Rad21 and Rec8 in mice: germ cell-specific expression of rec8 mRNA in both male and female mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rec8 gene of Schizosaccharomyces pombe is involved in linear element formation, chromosome pairing and sister-chromatid cohesion during meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol-induced meiotic maturation delay, spindle defects, and aneuploidy in mouse oocytes and zygotes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anaphase-promoting complex: new subunits and regulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cytogenetic study of G1-chromosomes in one-cell stage mouse embryo and in corresponding second polar body. Evaluation of aneuploidy originated in females heterozygous for translocation T[14;15]6Ca.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Securin is required for chromosomal stability in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,2-propanediol-induced premature centromere separation in mouse oocytes and aneuploidy in one-cell zygotes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of the proteasome: the lysis at the end of the tunnel

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of M-phase entry of prophase-blocked mouse oocytes through microinjection of okadaic acid, a specific phosphatase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulatory effect of okadaic acid, an inhibitor of protein phosphatases, on nuclear envelope breakdown and protein phosphorylation in mouse oocytes and one-cell embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential Role of Mitogen-Activated Protein Kinase in Pronuclear Envelope Assembly and Disassembly Following Fertilization of Mouse Eggs1

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid--a valuable new tool for the study of signal transduction and cell cycle regulation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C bands in human metaphase chromosomes treated by barium hydroxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteasome: a new target for novel drug therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sister chromatid separation in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects in components of the proteasome enhance transcriptional silencing at fission yeast centromeres and impair chromosome segregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sister chromatid cohesion and recombination in meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effect of okadaic acid on maturing mouse oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle control and cell division: implications for chemically induced carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid induces spindle lengthening and disrupts the interaction of microtubules with the kinetochores in metaphase II-arrested mouse oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consequences of non-extrusion of the first polar body and control of the sequential segregation of homologues and chromatids in mammalian oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid affects spindle organization in metaphase II-arrested rat oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The spindle checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased incidence of unpartnered single chromatids in metaphase II oocytes in 39,X(XO) mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metaphase-to-anaphase transition: avoiding a mid-life crisis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse Mos protooncogene product is present and functions during oogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of APC activity by phosphorylation and regulatory factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cohesin Rec8 is required for reductional chromosome segregation at meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predivision in human oocytes at meiosis I: a mechanism for trisomy formation in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of mitogen-activated protein kinase phosphorylation, microtubule organization, chromatin behavior, and cell cycle progression by protein phosphatases during pig oocyte maturation and fertilization in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postovulatory ageing of mouse oocytes in vivo and premature centromere separation and aneuploidy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance of meiotic arrest in mouse oocytes by purines: modulation of cAMP levels and cAMP phosphodiesterase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual inhibition of sister chromatid separation at metaphase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spo13 protects meiotic cohesin at centromeres in meiosis I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maternal age and trisomy--a unifying mechanism of formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazepam induces meiotic delay, aneuploidy and predivision of homologues and chromatids in mammalian oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that the endogenous histone H1 phosphatase in HeLa mitotic chromosomes is protein phosphatase 1, not protein phosphatase 2A

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mouse egg chromosome decondensation due to meiotic apparatus derangement induced by the protein phosphatase inhibitor, okadaic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the components of the putative mammalian sister chromatid cohesion complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the activity of type 2A protein phosphatases during meiotic maturation and the first mitotic cell cycle in mouse oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced premature G2/M-phase transition in pachytene spermatocytes includes events unique to meiosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytogenetic technique for mouse metaphase II oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slk19p is necessary to prevent separation of sister chromatids in meiosis I

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphorylation/dephosphorylation in the meiotic cell cycle of mammalian oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14516070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1024909119593

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44600629&oldid=2102542791"