(Q44606527)

1 July 2019

title

Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer (English)

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1 July 2019

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1

Magali Cucchiarini

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PubMed publication ID

4 December 2017

Ernest F Terwilliger

2

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1 July 2019

Dieter Kohn

series ordinal

3

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1 July 2019

Henning Madry

series ordinal

4

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1 July 2019

publication date

1 August 2009

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1 July 2019

Journal of Cellular and Molecular Medicine

published in

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1 July 2019

volume

13

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1 July 2019

issue

8B

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1 July 2019

page(s)

2476-2488

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1 July 2019

An introduction to the pathophysiology of osteoarthritis

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SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes.

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Sox9 is required for cartilage formation

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The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage

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Selective gene expression in brain microglia mediated via adeno-associated virus type 2 and type 5 vectors

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BALB/c 3T3 cells co-expressing FGF-2 and soluble FGF receptor acquire tumorigenicity

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Sex reversal by loss of the C-terminal transactivation domain of human SOX9

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Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system

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SOX9 directly regulates the type-II collagen gene

21 January 2018

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SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

21 January 2018

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SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

21 January 2018

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Resurfacing of articular cartilage explants with genetically-modified human chondrocytes in vitro

21 January 2018

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bFGF influences human articular chondrocyte differentiation.

21 January 2018

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Distribution of type X collagen mRNA in normal and osteoarthritic human cartilage

21 January 2018

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Activation of annexin II and V expression, terminal differentiation, mineralization and apoptosis in human osteoarthritic cartilage

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Basic FGF mediates an immediate response of articular cartilage to mechanical injury

21 January 2018

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Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00474.X

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation

21 January 2018

1 reference

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Gene therapy for cartilage defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00474.X

Degradative enzymes in osteoarthritis.

21 January 2018

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12 December 2020

Gene delivery to human chondrocytes by an adeno associated virus vector

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12 December 2020

Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis.

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12 December 2020

Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints

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12 December 2020

Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis

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12 December 2020

SOX9 exerts a bifunctional effect on type II collagen gene (COL2A1) expression in chondrocytes depending on the differentiation state

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12 December 2020

Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage

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12 December 2020

Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2

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12 December 2020

Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy

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12 December 2020

Adeno-associated vector mediated gene transfer of transforming growth factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism

1 reference

12 December 2020

Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9

1 reference

12 December 2020

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

1 reference

12 December 2020

Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data

1 reference

12 December 2020

Regulation of proliferation and osteochondrogenic differentiation of periosteum-derived cells by transforming growth factor-beta and basic fibroblast growth factor

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12 December 2020

Cytokines and inflammation in cartilage degradation.

1 reference

12 December 2020

Regulation of growth-plate chondrocytes by insulin-like growth-factor I and basic fibroblast growth factor

1 reference

12 December 2020

Effects of basic fibroblast growth factor, transforming growth factor-beta 1, insulin-like growth factor-1, and insulin on human osteoarthritic articular cartilage explants

1 reference

12 December 2020

Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector

1 reference

12 December 2020

Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage

1 reference

12 December 2020

10.1111/J.1582-4934.2008.00474.X

Identifiers

DOI

1 reference

1 July 2019

PMC publication ID

6512355

1 reference

1 July 2019

PubMed publication ID

18705695

1 reference

1 July 2019