(Q44618356)

English

Inhibition of Platelet-Activating Factor (PAF) Acetylhydrolase by Methyl Arachidonyl Fluorophosphonate Potentiates PAF Synthesis in Thrombin-Stimulated Human Coronary Artery Endothelial Cells

scientific article published on October 14, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Inhibition of platelet-activating factor (PAF) acetylhydrolase by methyl arachidonyl fluorophosphonate potentiates PAF synthesis in thrombin-stimulated human coronary artery endothelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Inhibition of Platelet-Activating Factor (PAF) Acetylhydrolase by Methyl Arachidonyl Fluorophosphonate Potentiates PAF Synthesis in Thrombin-Stimulated Human Coronary Artery Endothelial Cells (English)

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

0 references

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

molecular medicine

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

5

object named as

Jane McHowat

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560038

21 March 2024

author name string

Karin Wirsig

4

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Pamela J. Kell

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560038

21 March 2024

Michael H. Creer

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560038

21 March 2024

Kimberley N. Crown

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560038

21 March 2024

language of work or name

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publication date

14 October 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

full work available at URL

https://syndication.highwire.org/content/doi/10.1124/jpet.103.055392

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Journal of Pharmacology and Experimental Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

307

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1163-1170

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages.

1

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages

2

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Regulation of VEGF-induced endothelial cell PAF synthesis: role of p42/44 MAPK, p38 MAPK and PI3K pathways

3

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Metabolism of platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and 1-alkyl-2-acetyl-sn-glycerol by human endothelial cells

4

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

5

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase

6

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Evidence that methyl arachidonyl fluorophosphonate is an irreversible cannabinoid receptor antagonist

8

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools

9

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A2: structure-function studies with vesicle, micelle, and membrane assays1This paper is dedicated to the memory of Prof. H.M. Verheij.1

10

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Plasma degradation of platelet-activating factor in severely ill patients with clinical sepsis

11

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Induction of cyclo-oxygenase-2 expression by methyl arachidonyl fluorophosphonate in murine J774 macrophages: roles of protein kinase C, ERKs and p38 MAPK

13

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate

14

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

American Journal of Physiology

15

272

H1972

publication date

1997

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Thrombin activates a membrane-associated calcium-independent PLA2 in ventricular myocytes.

16

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Calcium-independent phospholipase A2 in isolated rabbit ventricular myocytes

17

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Endothelial cell PAF synthesis following thrombin stimulation utilizes Ca(2+)-independent phospholipase A(2).

18

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children

19

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Role of platelet-activating factor in cardiovascular pathophysiology.

20

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Sol Sherry lecture in thrombosis: molecular events in acute inflammation

21

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2

22

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

The expanding superfamily of phospholipase A(2) enzymes: classification and characterization

23

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Platelet-activating factor: the biosynthetic and catabolic enzymes

24

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Platelet-activating factor acetylhydrolases

25

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma

26

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Mammalian platelet-activating factor acetylhydrolases

27

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Release of acetylhydrolase from platelets on aggregation with platelet-activating factor

28

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Release of platelet-activating factor in systemic lupus erythematosus

29

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad

30

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Human platelets stimulated by thrombin produce platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when the degrading enzyme acetyl hydrolase is blocked

31

1 reference

10.1124/JPET.103.055392

https://api.crossref.org/works/10.1124/JPET.103.055392

21 March 2024

Identifiers

10.1124/JPET.103.055392

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

ResearchGate publication ID

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