(Q44621043)

English

15-Deoxy-Δ-12-14-PGJ2 Regulates Apoptosis Induction and Nuclear Factor-κB Activation Via a Peroxisome Proliferator-Activated Receptor-γ–Independent Mechanism in Hepatocellular Carcinoma

scientific article published on October 1, 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 December 2017

15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

15-Deoxy-Δ-12-14-PGJ2 Regulates Apoptosis Induction and Nuclear Factor-κB Activation Via a Peroxisome Proliferator-Activated Receptor-γ–Independent Mechanism in Hepatocellular Carcinoma (English)

1 reference

10.1097/01.LAB.0000092233.50246.F7

https://api.crossref.org/works/10.1097/01.LAB.0000092233.50246.F7

22 March 2024

1 reference

10.1097/01.LAB.0000092233.50246.F7

https://api.crossref.org/works/10.1097/01.LAB.0000092233.50246.F7

22 March 2024

author name string

Hiroshi Okano

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Katsuya Shiraki

2

1 reference

Europe PubMed Central

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4 December 2017

Hidekazu Inoue

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Yutaka Yamanaka

4

1 reference

Europe PubMed Central

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4 December 2017

Tomoyuki Kawakita

5

1 reference

Europe PubMed Central

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4 December 2017

Yukiko Saitou

6

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Yumi Yamaguchi

7

1 reference

Europe PubMed Central

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4 December 2017

Naoyuki Enokimura

8

1 reference

Europe PubMed Central

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4 December 2017

Norihiko Yamamoto

9

1 reference

Europe PubMed Central

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4 December 2017

Kazushi Sugimoto

10

1 reference

Europe PubMed Central

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4 December 2017

Kazumoto Murata

11

1 reference

Europe PubMed Central

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4 December 2017

Takeshi Nakano

12

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Europe PubMed Central

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4 December 2017

language of work or name

1 reference

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publication date

1 October 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

full work available at URL

http://www.laboratoryinvestigation.org/article/S0023683722034754/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14563954

22 March 2024

https://api.elsevier.com/content/article/PII:S0023683722034754?httpAccept=text/xml

1 reference

10.1097/01.LAB.0000092233.50246.F7

https://api.crossref.org/works/10.1097/01.LAB.0000092233.50246.F7

22 March 2024

https://api.elsevier.com/content/article/PII:S0023683722034754?httpAccept=text/plain

1 reference

10.1097/01.LAB.0000092233.50246.F7

https://api.crossref.org/works/10.1097/01.LAB.0000092233.50246.F7

22 March 2024

Laboratory Investigation

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

83

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

1529-1539

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1 reference

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21 January 2018

15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways.

1 reference

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21 January 2018

Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis

1 reference

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21 January 2018

Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha.

1 reference

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21 January 2018

Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

PPAR activators inhibit endothelial cell migration by targeting Akt.

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Hostile takeovers: viral appropriation of the NF-kB pathway

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Effects of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on the expression of inflammatory cytokines and apoptosis induction in rheumatoid synovial fibroblasts and monocytes

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

NF-kappaB signals induce the expression of c-FLIP.

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Macrophages resistant to endogenously generated nitric oxide-mediated apoptosis are hypersensitive to exogenously added nitric oxide donors: dichotomous apoptotic response independent of caspase 3 and reversal by the mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Peroxisome proliferator-activated receptor gamma augments tumor necrosis factor family-induced apoptosis in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Role of Bcl-2 family members in caspase-independent apoptosis during Chlamydia infection.

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

The emerging role of caspase inhibitors in gastrointestinal cancers

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

A ligand for peroxisome proliferator activated receptor gamma inhibits cell growth and induces apoptosis in human liver cancer cells

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Bcl-2 family: life-or-death switch

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

A low-molecular-weight fraction of human seminal plasma activates adenylyl cyclase and induces caspase 3-independent apoptosis in prostatic epithelial cells by decreasing mitochondrial potential and Bcl-2/Bax ratio

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Ras signaling is involved in the expression of Fas-L in glioma.

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells

1 reference

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21 January 2018

Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Regulation of TRAIL-induced apoptosis by transcription factors

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

15-Deoxy-Delta(12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptor-gamma, induces apoptosis in JEG3 choriocarcinoma cells

1 reference

https://api.crossref.org/works/10.1097%2F01.LAB.0000092233.50246.F7

21 January 2018

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

1 reference

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TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria

1 reference

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21 January 2018

Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis

1 reference

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21 January 2018

NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells.

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10.1097/01.LAB.0000092233.50246.F7

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22 March 2024

Inhibition of constitutive NF-kappa B activity suppresses tumorigenicity of Ewing sarcoma EW7 cells.

20

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22 March 2024

15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.

29

1 reference

10.1097/01.LAB.0000092233.50246.F7

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22 March 2024

Identifiers

10.1097/01.LAB.0000092233.50246.F7

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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