(Q44630376)

4 December 2017

title

Molecular basis for atovaquone resistance in Pneumocystis jirovecii modeled in the cytochrome bc(1) complex of Saccharomyces cerevisiae (English)

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4 December 2017

main subject

Saccharomyces cerevisiae

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based on heuristic

inferred from title

Pneumocystis jirovecii

object named as

Pneumocystis jirovecii

1 reference

4

Steven R Meshnick

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4 December 2017

6

Bernard L Trumpower

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4 December 2017

Jacques J Kessl

1

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4 December 2017

Philip Hill

series ordinal

2

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4 December 2017

Benjamin B Lange

series ordinal

3

1 reference

4 December 2017

Brigitte Meunier

series ordinal

5

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4 December 2017

language of work or name

English

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publication date

23 October 2003

1 reference

Journal of Biological Chemistry

4 December 2017

published in

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4 December 2017

volume

279

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4 December 2017

issue

4

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4 December 2017

page(s)

2817-2824

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Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Efficacy of a hydroxynaphthoquinone, 566C80, in experimental Pneumocystis carinii pneumonitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Atovaquone suspension compared with aerosolized pentamidine for prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected subjects intolerant of trimethoprim or sulfonamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Sequence polymorphisms in the Pneumocystis carinii cytochrome b gene and their association with atovaquone prophylaxis failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Pneumocystis carinii cytochrome b mutations are associated with atovaquone exposure in patients with AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Molecular basis for atovaquone binding to the cytochrome bc1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Evolutionary relationships within the fungi: analyses of nuclear small subunit rRNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Effects of pentamidine isethionate on Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Plasmids can stably transform yeast mitochondria lacking endogenous mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Recapitulation in Saccharomyces cerevisiae of cytochrome b mutations conferring resistance to atovaquone in Pneumocystis jiroveci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Ubiquinone at center N is responsible for triphasic reduction of cytochrome b in the cytochrome bc(1) complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Protein-protein interactions between cytochrome b and the Fe-S protein subunits during QH2 oxidation and large-scale domain movement in the bc1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Inhibitory analogs of ubiquinol act anti-cooperatively on the Yeast cytochrome bc1 complex. Evidence for an alternating, half-of-the-sites mechanism of ubiquinol oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Mutational analysis of the mouse mitochondrial cytochrome b gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Atovaquone Compared with Dapsone for the Prevention ofPneumocystis cariniiPneumonia in Patients with HIV Infection Who Cannot Tolerate Trimethoprim, Sulfonamides, or Both

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Studies on the effect of stigmatellin derivative on cytochrome band the Rieske iron-sulfur cluster of cytochrome c reductase from bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Diving: occupation or physiological experiment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Successful prevention and treatment of babesiosis with atovaquone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Transformation of Saccharomyces cerevisiae mitochondria using the biolistic gun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Genetic transformation of Saccharomyces cerevisiae mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

Purification of highly active cytochrome bc1 complexes from phylogenetically diverse species by a single chromatographic procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309984200

21 January 2018

Identifiers

DOI

10.1074/JBC.M309984200

1 reference

4 December 2017

1 reference