(Q44630513)

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Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations.

scientific article published on 10 May 2013

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

tolfenamic acid

1 reference

ChEBI release 2020-05-28

Anette Müllertz

10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Colin W. Pouton

11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Christopher J.H. Porter

12

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Hywel D Williams

1

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Europe PubMed Central

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1 March 2020

Philip Sassene

2

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Europe PubMed Central

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1 March 2020

Karen Kleberg

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Marilyn Calderone

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Annabel Igonin

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Eduardo Jule

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jan Vertommen

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Ross Blundell

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Hassan Benameur

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

LFCS Consortium

13

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Europe PubMed Central

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1 March 2020

publication date

10 May 2013

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Europe PubMed Central

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1 March 2020

Pharmaceutical Research

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

30

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Europe PubMed Central

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1 March 2020

12

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

3059-3076

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23661145%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

1 reference

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Strategies to address low drug solubility in discovery and development.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Enhancing intestinal drug solubilisation using lipid-based delivery systems.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Lipid formulation strategies for enhancing intestinal transport and absorption of P-glycoprotein (P-gp) substrate drugs: in vitro/in vivo case studies

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The effects of excipients on transporter mediated absorption

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

The effect of oral lipids and circulating lipoproteins on the metabolism of drugs

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Lipid-based formulations for intestinal lymphatic delivery

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug delivery systems.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Characterization and optimization of AMG 517 supersaturatable self-emulsifying drug delivery system (S-SEDDS) for improved oral absorption

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system.

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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Use of a dynamic in vitro lipolysis model to rationalize oral formulation development for poor water soluble drugs: correlation with in vivo data and the relationship to intra-enterocyte processes in rats

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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Chromatographic retention of drug molecules on immobilised liposomes prepared from egg phospholipids and from chemically pure phospholipids

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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Ethanol effects on apparent solubility of poorly soluble drugs in simulated intestinal fluid.

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Understanding the solid-state forms of fenofibrate--a spectroscopic and computational study

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Characterization of two polymorphic forms of tolfenamic acid, N-(2-methyl-3-chlorophenyl)anthranilic acid: their crystal structures and relative stabilities

1 reference

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1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Thermodynamic and structural study of tolfenamic acid polymorphs.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Separation and characterization of the colloidal phases produced on digestion of common formulation lipids and assessment of their impact on the apparent solubility of selected poorly water-soluble drugs.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Effect of molecular weight, temperature, and additives on the moisture sorption properties of polyethylene glycol

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TowardIn SilicoPrediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Drug precipitation-permeation interplay: supersaturation in an absorptive environment

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Evaluation of gastrointestinal drug supersaturation and precipitation: strategies and issues.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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Protein purification by bulk crystallization: the recovery of ovalbumin

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Inhibition of solution crystal growth of ritonavir by cellulose polymers – factors influencing polymer effectiveness

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Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

21 January 2018

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

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https://api.crossref.org/works/10.1007%2FS11095-013-1038-Z

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A classification system to assess the crystallization tendency of organic molecules from undercooled melts.

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Trends in solubility of polymorphs

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https://pubmed.ncbi.nlm.nih.gov/23661145

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Dissolution enhancement of fenofibrate by micronization, cogrinding and spray-drying: comparison with commercial preparations

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https://pubmed.ncbi.nlm.nih.gov/23661145

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