(Q44635089)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17616522%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Conserved residue Lys574 in the cavity of HIV-1 Gp41 coiled-coil domain is critical for six-helix bundle stability and virus entry (English)

1 reference

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1 January 2020

8

1 reference

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1 January 2020

9

Shibo Jiang

1 reference

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1 January 2020

3

Weiguo Jing

1 reference

1 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17616522%20AND%20SRC:MED&resulttype=core&format=json

author name string

Yuxian He

1

1 reference

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1 January 2020

Shuwen Liu

2

1 reference

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1 January 2020

Hong Lu

4

1 reference

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1 January 2020

Dongmei Cai

5

1 reference

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1 January 2020

Darin Jeekin Chin

6

1 reference

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1 January 2020

Asim K Debnath

7

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1 January 2020

language of work or name

English

0 references

publication date

6 July 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17616522%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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1 January 2020

volume

282

1 reference

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1 January 2020

issue

35

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1 January 2020

page(s)

25631-25639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17616522%20AND%20SRC:MED&resulttype=core&format=json

The Role of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins in Virus Infection

1 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Mechanisms of viral membrane fusion and its inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Core structure of gp41 from the HIV envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

HIV entry and its inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Structure-function studies of the self-assembly domain of the human immunodeficiency virus type 1 transmembrane protein gp41.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Structural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

N- and C-domains of HIV-1 gp41: mutation, structure and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

A salt bridge between an N-terminal coiled coil of gp41 and an antiviral agent targeted to the gp41 core is important for anti-HIV-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Biophysical characterization of the structure of the amino-terminal region of gp41 of HIV-1. Implications on viral fusion mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Atomic structure of the ectodomain from HIV-1 gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Genetic evidence that interhelical packing interactions in the gp41 core are critical for transition of the human immunodeficiency virus type 1 envelope glycoprotein to the fusion-active state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

High throughput screening and characterization of HIV-1 entry inhibitors targeting gp41: theories and techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Phosphorothioate oligonucleotides inhibit human immunodeficiency virus type 1 fusion by blocking gp41 core formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703781200

21 January 2018

Identifiers

DOI

10.1074/JBC.M703781200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17616522%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference