(Q44637149)

4 December 2017

title

Insulin regulation of heart function in aging fruit flies (English)

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4 December 2017

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James R Cypser

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Marc Tatar

object named as

Marc Tatar

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author name string

Robert J Wessells

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4 December 2017

Erin Fitzgerald

2

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4 December 2017

Rolf Bodmer

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4 December 2017

language of work or name

English

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publication date

21 November 2004

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4 December 2017

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4 December 2017

volume

36

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4 December 2017

issue

12

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4 December 2017

page(s)

1275-1281

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Genetic pathways that regulate ageing in model organisms

4 December 2017

cites work

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7 January 2021

Molecular genetics of aging in the fly: is this the end of the beginning?

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7 January 2021

The endocrine regulation of aging by insulin-like signals

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7 January 2021

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

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7 January 2021

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

1 reference

7 January 2021

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

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7 January 2021

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease

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7 January 2021

Age-associated cardiac dysfunction in Drosophila melanogaster

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7 January 2021

Screening assays for heart function mutants in Drosophila.

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7 January 2021

Heart development in Drosophila and its relationship to vertebrates.

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7 January 2021

A congenital heart defect in Drosophila caused by an action-potential mutation.

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7 January 2021

Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system

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7 January 2021

The demography of slow aging in male and female Drosophila mutant for the insulin-receptor substrate homologue chico.

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7 January 2021

Growth control: invertebrate insulin surprises!

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7 January 2021

Genetic control of cell size

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7 January 2021

Genetic analysis of insulin signaling in Drosophila

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7 January 2021

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

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7 January 2021

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

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7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

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7 January 2021

Innervation of the ring gland of Drosophila melanogaster

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7 January 2021

Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes

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7 January 2021

Regulation of lifespan by sensory perception in Caenorhabditis elegans

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7 January 2021

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

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7 January 2021

A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span

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7 January 2021

Impaired ovarian ecdysone synthesis of Drosophila melanogaster insulin receptor mutants

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7 January 2021

Extended longevity in mice lacking the insulin receptor in adipose tissue

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7 January 2021

Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan

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7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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7 January 2021

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

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7 January 2021

The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

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7 January 2021

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

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7 January 2021

The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential

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7 January 2021

Ostia, the inflow tracts of the Drosophila heart, develop from a genetically distinct subset of cardial cells

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7 January 2021

atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain

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7 January 2021

Identifiers

DOI

10.1038/NG1476

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4 December 2017

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