(Q44638678)

reason for preferred rank

4 December 2017

title

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck (English)

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

27 March 2024

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

27 March 2024

pharmaceutical science

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

27 March 2024

author name string

John Wityak

1

1 reference

4 December 2017

Jagabandhu Das

2

1 reference

4 December 2017

Zhongqi Shen

4

1 reference

4 December 2017

James Lin

5

1 reference

4 December 2017

Ping Chen

6

1 reference

4 December 2017

Sidney Pitt

8

1 reference

4 December 2017

Suhong Pang

9

1 reference

4 December 2017

Ding Ren Shen

10

1 reference

4 December 2017

Qiong Fang

11

1 reference

4 December 2017

Robert V. Moquin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

Arthur M. Doweyko

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

Henry F. de Fex

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

Gary L. Schieven

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

Steven B. Kanner

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

Joel C. Barrish

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592495

27 March 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

4 December 2017

17 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14592495

full work available at URL

27 March 2024

https://api.elsevier.com/content/article/PII:S0960894X03009156?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

https://api.elsevier.com/content/article/PII:S0960894X03009156?httpAccept=text/plain

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Bioorganic & Medicinal Chemistry Letters

27 March 2024

published in

1 reference

4 December 2017

volume

13

1 reference

4 December 2017

issue

22

1 reference

4 December 2017

page(s)

4007-4010

1 reference

Profound block in thymocyte development in mice lacking p56lck

4 December 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

27 March 2024

3

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

27 March 2024

4

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Signal transduction by lymphocyte antigen receptors

27 March 2024

5

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

27 March 2024

6

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

27 March 2024

7

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Allo-skin graft rejection, tumor rejection and natural killer activity in mice lacking p56lck

27 March 2024

8

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56(Lck).

27 March 2024

13

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Synthesis and SAR of novel imidazoquinoxaline-based Lck inhibitors: improvement of cell potency

27 March 2024

14

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Molecular design, synthesis, and structure-Activity relationships leading to the potent and selective p56(lck) inhibitor BMS-243117.

27 March 2024

15

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56(lck) inhibitors

27 March 2024

16

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Structure and expression of lck transcripts in human lymphoid cells

27 March 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA.

27 March 2024

18

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.

27 March 2024

20

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

27 March 2024

21

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

27 March 2024

22

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.054

27 March 2024

Identifiers

1 reference

4 December 2017

1 reference