(Q44644550)

5 December 2017

title

Selective and nonselective toxicity of TRAIL/Apo2L combined with chemotherapy in human bone tumour cells vs. normal human cells (English)

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5 December 2017

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5 December 2017

Klaus-Michael Debatin

7

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5 December 2017

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Christopher Poremba

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5 December 2017

5

Marc Hotfilder

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5 December 2017

Frans Van Valen

1

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5 December 2017

Karl-Ludwig Schäfer

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5 December 2017

Borna Truckenbrod

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5 December 2017

Winfried Winkelmann

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5 December 2017

language of work or name

English

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publication date

1 December 2003

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International Journal of Cancer

5 December 2017

published in

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5 December 2017

volume

107

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5 December 2017

issue

6

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5 December 2017

page(s)

929-940

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The role of chemotherapy in osteogenic sarcoma

5 December 2017

cites work

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Identification and characterization of a new member of the TNF family that induces apoptosis

21 January 2018

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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

21 January 2018

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

1 reference

Safety and antitumor activity of recombinant soluble Apo2 ligand

21 January 2018

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Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

21 January 2018

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells

21 January 2018

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Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL).

21 January 2018

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Forskolin inhibition of glucose transport in bone cell cultures through a cAMP-independent mechanism.

21 January 2018

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FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

21 January 2018

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Inhibition of death receptor signals by cellular FLIP

21 January 2018

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IAP family proteins--suppressors of apoptosis

21 January 2018

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Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

21 January 2018

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Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis.

21 January 2018

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Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types

21 January 2018

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Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

21 January 2018

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p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4.

21 January 2018

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Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.

21 January 2018

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Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL

21 January 2018

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Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression.

21 January 2018

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Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

21 January 2018

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TRAIL: a molecule with multiple receptors and control mechanisms

21 January 2018

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Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

21 January 2018

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Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

21 January 2018

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Avoiding premature apoptosis of normal epidermal cells

21 January 2018

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Telomerase activity and telomerase subunits gene expression patterns in neuroblastoma: a molecular and immunohistochemical study establishing prognostic tools for fresh-frozen and paraffin-embedded tissues

21 January 2018

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Human osteoblasts are resistant to Apo2L/TRAIL-mediated apoptosis

21 January 2018

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How TRAIL kills cancer cells, but not normal cells

21 January 2018

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Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP

21 January 2018

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Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.11503

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5 December 2017

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