(Q44650481)

English

The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1

scientific article published on November 10, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1 (English)

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most precise value

1 reference

10.1074/JBC.M310412200

https://api.crossref.org/works/10.1074/JBC.M310412200

31 March 2024

The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-beta1 (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610066

31 March 2024

1 reference

based on heuristic

inferred from title

signal transduction

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610066

31 March 2024

1 reference

10.1074/JBC.M310412200

https://api.crossref.org/works/10.1074/JBC.M310412200

31 March 2024

1 reference

10.1074/JBC.M310412200

https://api.crossref.org/works/10.1074/JBC.M310412200

31 March 2024

author name string

Anne-Christine Poncelet

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Constance E. Runyan

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610066

31 March 2024

H. William Schnaper

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610066

31 March 2024

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publication date

10 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

full work available at URL

http://www.jbc.org/article/S0021925818526296/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610066

31 March 2024

https://api.elsevier.com/content/article/PII:S0021925818526296?httpAccept=text/xml

1 reference

10.1074/JBC.M310412200

https://api.crossref.org/works/10.1074/JBC.M310412200

31 March 2024

https://api.elsevier.com/content/article/PII:S0021925818526296?httpAccept=text/plain

1 reference

10.1074/JBC.M310412200

https://api.crossref.org/works/10.1074/JBC.M310412200

31 March 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.M310412200

1 reference

10.1074/JBC.M310412200

https://api.crossref.org/works/10.1074/JBC.M310412200

31 March 2024

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

2632-2639

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

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Specificity, diversity, and regulation in TGF-beta superfamily signaling.

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Smads as transcriptional co-modulators

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Transcriptional control by the TGF-beta/Smad signaling system

5

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31 March 2024

Signaling by distinct classes of phosphoinositide 3-kinases

6

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31 March 2024

The phosphoinositide 3-kinase pathway

8

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Phosphatidylinositol 3-kinase is required for growth factor-induced amino acid uptake by vascular smooth muscle cells

10

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31 March 2024

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

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Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.

12

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Activin signaling pathways in ovine pituitary and LbetaT2 gonadotrope cells.

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31 March 2024

TGF-beta 1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells

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31 March 2024

The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells

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31 March 2024

Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells

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31 March 2024

Regulation of human mesangial cell collagen expression by transforming growth factor-beta1

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31 March 2024

Human Smad3 and Smad4 are sequence-specific transcription activators

18

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31 March 2024

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

19

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31 March 2024

The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain

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31 March 2024

Cloning and characterization of five overlapping cDNAs specific for the human proα 1(I) collagen chain

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31 March 2024

Structure of a cDNA for the pro alpha 2 chain of human type I procollagen. Comparison with chick cDNA for pro alpha 2(I) identifies structurally conserved features of the protein and the gene

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31 March 2024

Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase

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31 March 2024

The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression

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PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF

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31 March 2024

Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells

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Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

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A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

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Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells

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Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription

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Regulation of Smad signaling by protein kinase C

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Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

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Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.

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Phosphatidylinositol 3-kinase-dependent stabilization of alpha1(I) collagen mRNA in human lung fibroblasts

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TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression

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Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival

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Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

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Identifiers

10.1074/JBC.M310412200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

release_m4i5xg3dkza33n6s2vsrq4otre

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https://api.fatcat.wiki/v0/release/m4i5xg3dkza33n6s2vsrq4otre

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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