(Q44650493)

English

12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione

scientific article published on 10 November 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 December 2017

12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione (English)

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Europe PubMed Central

PubMed publication ID

5 December 2017

arsenic trioxide

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Patricia Sancho

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Patricia Sancho

3

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6

object named as

Patricio Aller

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Europe PubMed Central

PubMed publication ID

5 December 2017

author name string

Carlos Fernández

1

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Europe PubMed Central

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5 December 2017

Adrián M Ramos

2

1 reference

Europe PubMed Central

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5 December 2017

Donna Amrán

4

1 reference

Europe PubMed Central

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5 December 2017

Elena de Blas

5

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Europe PubMed Central

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5 December 2017

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publication date

10 November 2003

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5 December 2017

number of pages

8

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Journal of Biological Chemistry

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5 December 2017

279

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5 December 2017

5

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Europe PubMed Central

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5 December 2017

3877-3884

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Europe PubMed Central

PubMed publication ID

5 December 2017

Arsenic compounds as anticancer agents

1 reference

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Serine/threonine protein kinases and apoptosis.

1 reference

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Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line

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The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.

1 reference

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Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8

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Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation

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MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells

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Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways

1 reference

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Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death

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Requirement for ERK activation in cisplatin-induced apoptosis

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Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade

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21 January 2018

Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.

1 reference

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Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases

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21 January 2018

Apoptosis induced by arsenic trioxide in leukemia U937 cells is dependent on activation of p38, inactivation of ERK and the Ca2+-dependent production of superoxide

1 reference

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Establishment and characterization of a human histiocytic lymphoma cell line (U-937)

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

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21 January 2018

Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells

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21 January 2018

The induction of vimentin gene expression by sodium butyrate in human promonocytic leukemia U937 cells.

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21 January 2018

Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation

1 reference

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21 January 2018

Modulation of ornithine decarboxylase gene transcript levels by differentiation inducers in human promyelocytic leukemia HL60 cells.

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21 January 2018

Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.

1 reference

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21 January 2018

Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937).

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21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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21 January 2018

Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells

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21 January 2018

The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding

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21 January 2018

Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia

1 reference

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21 January 2018

Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3

1 reference

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21 January 2018

Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death

1 reference

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21 January 2018

Reactions of arsenic(III) and arsenic(V) species with glutathione

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21 January 2018

Cyclosporin A-sensitive permeability transition pore is involved in Cd(2+)-induced dysfunction of isolated rat liver mitochondria: doubts no more.

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21 January 2018

Cellular glutathione and thiols metabolism.

1 reference

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21 January 2018

Retrodifferentiation and cell death.

1 reference

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21 January 2018

Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells

1 reference

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21 January 2018

Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase

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Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways

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21 January 2018

Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase

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Glutathione and metallothioneins as cellular defense against cadmium toxicity in cultured Chinese hamster cells

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Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

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21 January 2018

Identifiers

10.1074/JBC.M310665200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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