(Q44655985)

5 December 2017

title

The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking (English)

1 reference

5 December 2017

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

2 April 2024

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

2 April 2024

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

2 April 2024

author name string

Jessie Zhang

1

1 reference

5 December 2017

Nicole Dudley-Rucker

2

1 reference

5 December 2017

Elvira Lopez-Perez

4

1 reference

5 December 2017

Marc Issandou

5

1 reference

5 December 2017

Jan R. Crowley

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617742

2 April 2024

Jean E. Schaffer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617742

2 April 2024

Daniel S. Ory

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617742

2 April 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14617742

2 April 2024

publication date

16 November 2003

1 reference

full work available at URL

5 December 2017

http://www.jlr.org/article/S0022227520318939/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617742

https://api.elsevier.com/content/article/PII:S0022227520318939?httpAccept=text/xml

2 April 2024

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

https://api.elsevier.com/content/article/PII:S0022227520318939?httpAccept=text/plain

2 April 2024

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

https://syndication.highwire.org/content/doi/10.1194/jlr.M300409-JLR200

2 April 2024

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

Journal of Lipid Research

2 April 2024

published in

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5 December 2017

volume

45

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5 December 2017

issue

2

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5 December 2017

page(s)

223-231

1 reference

Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes

5 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

SCAP ligands are potent new lipid-lowering drugs

21 January 2018

1 reference

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Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Niemann-Pick type C: a disorder of cellular cholesterol trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Identification of HE1 as the second gene of Niemann-Pick C disease

21 January 2018

1 reference

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The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Complementation studies in Niemann-Pick disease type C indicate the existence of a second group

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Oxysterol biosynthetic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Co-cultivation of Niemann-Pick disease type C fibroblasts belonging to complementation groups alpha and beta stimulates LDL-derived cholesterol esterification

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M300409-JLR200

The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one

21 January 2018

4

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

Cholesterol transport from plasma membranes to intracellular membranes is inhibited by 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one

2 April 2024

5

1 reference

https://api.crossref.org/works/10.1194/JLR.M300409-JLR200

2 April 2024

Identifiers

1 reference

5 December 2017

1 reference