(Q44702888)

5 December 2017

Endoplasmic reticulum-localized amyloid beta-peptide is degraded in the cytosol by two distinct degradation pathways (English)

1 reference

5 December 2017

endoplasmic reticulum

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author

Markus P Kummer

series ordinal

3

1 reference

5 December 2017

Anton Schmitz

1

1 reference

PubMed ID

14690498

5 December 2017

Andrea Schneider

series ordinal

2

1 reference

PubMed ID

14690498

5 December 2017

Volker Herzog

series ordinal

4

1 reference

5 December 2017

1 February 2004

1 reference

5 December 2017

1 reference

5 December 2017

5

1 reference

5 December 2017

89-101

1 reference

5 December 2017

2

1 reference

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

5 December 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Role of Cue1p in ubiquitination and degradation at the ER surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Aggresomes: a cellular response to misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Cholera toxin is exported from microsomes by the Sec61p complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Presenilins are not required for A beta 42 production in the early secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Cytosolic and nuclear aggregation of the amyloid beta-peptide following its expression in the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Insulin degradation: progress and potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

The protein translocation channel mediates glycopeptide export across the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Genetic variation in a haplotype block spanningIDE influences Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

Preparation of microsomal membranes for cotranslational protein translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00159.X

10.1111/J.1600-0854.2004.00159.X

21 January 2018

Identifiers

DOI

1 reference

5 December 2017

1 reference

PubMed ID

14690498