(Q44713444)

5 December 2017

title

A global increase in 5-hydroxymethylcytosine levels marks osteoarthritic chondrocytes (English)

1 reference

5 December 2017

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Sarah E B Taylor

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Lakshmi Dhulipala

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Madhusikta Rath

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Nidhi Bhutani

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

1 January 2014

1 reference

5 December 2017

published in

Arthritis & Rheumatology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

1

1 reference

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1 June 2020

page(s)

90-100

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449578%20AND%20SRC:MED&resulttype=core&format=json

Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis

1 June 2020

cites work

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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DNA demethylation dynamics

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

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Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

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Reprogramming towards pluripotency requires AID-dependent DNA demethylation

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

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Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

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TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

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Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

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Editorial: More evidence for a role of CpG methylation in the pathogenesis of osteoarthritis

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DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

21 January 2018

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Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

21 January 2018

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cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.

21 January 2018

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Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation.

21 January 2018

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Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.

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Effects of intermittent hydrostatic pressure and BMP‐2 on osteoarthritic human chondrocyte metabolism in vitro

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Genetic and epigenetic mechanisms combine to control MMP1 expression and its association with preterm premature rupture of membranes

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Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites

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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

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