(Q44720869)

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Agonist concentration-dependent differential responsivity of a human platelet purinergic receptor: pharmacological and kinetic studies of aggregation, deaggregation and shape change responses mediated by the purinergic P2Y1 receptor in vitro

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Europe PubMed Central

PubMed publication ID

5 December 2017

Agonist concentration-dependent differential responsivity of a human platelet purinergic receptor: pharmacological and kinetic studies of aggregation, deaggregation and shape change responses mediated by the purinergic P2Y1 receptor in vitro (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

author name string

Saul Maayani

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Todd E Schwarz

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Nayana D Patel

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Barbara D Craddock-Royal

4

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Europe PubMed Central

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5 December 2017

Thomas M Tagliente

5

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Europe PubMed Central

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5 December 2017

publication date

1 November 2003

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Europe PubMed Central

PubMed publication ID

5 December 2017

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Europe PubMed Central

PubMed publication ID

5 December 2017

14

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Europe PubMed Central

PubMed publication ID

5 December 2017

7-8

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

445-462

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets

1 reference

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21 January 2018

Effects of P2Y(1) and P2Y(12) receptor antagonists on platelet aggregation induced by different agonists in human whole blood

1 reference

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21 January 2018

Hereditary defect in the platelet release reaction caused by a deficiency in the storage pool of platelet adenine nucleotides

1 reference

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21 January 2018

Secretable Storage Pools in Platelets

1 reference

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21 January 2018

The integrin alpha IIb/beta 3 in human platelet signal transduction

1 reference

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21 January 2018

Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

1 reference

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21 January 2018

ADP can induce aggregation of human platelets via both P2Y(1) and P(2T) receptors

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Concurrent responses elicited by isolated activation of platelet G q -coupled receptors, in vitro : a novel approach for their separation and analysis

1 reference

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21 January 2018

The balance of concurrent aggregation and deaggregation processes in platelets is linked to differential occupancy of ADP receptor subtypes

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Deaggregation is an integral component of the response of platelets to ADP in vitro: kinetic studies of literature and original data

1 reference

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21 January 2018

Activation of the alpha(2A)-adrenoceptor mediates deceleration of the deaggregation component of the response to ADP or 5-HT in human platelets in vitro

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Activation of Gi-coupled receptors releases a tonic state of inhibited platelet aggregation

1 reference

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21 January 2018

Detection of platelet aggregates with a particle counting method using light scattering.

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

2-Methylthioadenosine[beta-32P]diphosphate. An agonist and radioligand for the receptor that inhibits the accumulation of cyclic AMP in intact blood platelets

1 reference

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21 January 2018

A compartmental model of platelet aggregation in vitro: the kinetics of single platelets.

1 reference

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21 January 2018

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

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21 January 2018

Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Role of catecholamines in platelet function: pathophysiological and clinical significance

1 reference

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21 January 2018

Potentiation of aggregation and inhibition of adenylate cyclase in human platelets by prostaglandin E analogues

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Platelet prostanoid receptors

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

2-Methylthioadenosine-5′-phosphate: a Specific Inhibitor of Platelet Aggregation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Identification of the platelet ADP receptor targeted by antithrombotic drugs

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Molecular and biochemical evidence for the presence of type III adenylyl cyclase in human platelets

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Relationship between phosphorylation of blood platelet proteins and secretion of platelet granule constituents I. Effects of different aggregating agents

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Diversity of signaling underlying responses mediated by selective activation of the platelet thromboxane A 2 (TXA 2 ) receptor; pharmacological and kinetic studies in vitro

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

The role of heterotrimeric G proteins in platelet activation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Rapid desensitization of the serotonin(2C) receptor system: effector pathway and agonist dependence

1 reference

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21 January 2018

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets.

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves

1 reference

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21 January 2018

Heptahelical receptor signaling: beyond the G protein paradigm.

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction

1 reference

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21 January 2018

G-protein-coupled receptors and signaling networks: emerging paradigms.

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Protein-protein interactions at G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation

1 reference

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21 January 2018

A type II phosphoinositide 3-kinase is stimulated via activated integrin in platelets. A source of phosphatidylinositol 3-phosphate

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Effects of a P2Y(12) receptor antagonist on the response of equine platelets to ADP. Comparison with human platelets

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Thrombin-receptor agonist peptides, in contrast to thrombin itself, are not full agonists for activation and signal transduction in human platelets in the absence of platelet-derived secondary mediators

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding

1 reference

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21 January 2018

An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

ADP receptors and clinical bleeding disorders

1 reference

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21 January 2018

Increased bleeding tendency and decreased susceptibility to thromboembolism in mice lacking the prostaglandin E receptor subtype EP(3).

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

The central role of the P2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

alpha(2A)-adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Formation of PI 3-kinase products in platelets by thrombin, but not collagen, is dependent on synergistic autocrine stimulation, particularly through secreted ADP

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Role of autocrine stimulation for the effects of cyclic AMP on protein and lipid phosphorylation in platelets activated by particles

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Role of autocrine stimulation on the effects of cyclic AMP on protein and lipid phosphorylation in collagen-activated and thrombin-activated platelets

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Evidence for functional 5-HT2 receptor sites on human blood platelets

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

THE AGGREGATION OF BLOOD PLATELETS

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Binding of 2-azidoadenosine [beta-32P]diphosphate to the receptor on intact human blood platelets which inhibits adenylate cyclase

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

ADP-induced platelet shape change: an investigation of the signalling pathways involved and their dependence on the method of platelet preparation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

cAMP is not an important messenger for ADP-induced platelet aggregation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Influence of apyrase on stability of suspensions of washed rabbit platelets

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

ADP-induced refractory state of platelets in vitro. I. Methodological studies on aggregation in platelet rich plasma

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Interactions between effectors linked to serotonin receptors

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Pleiotropic behavior of 5-HT2A and 5-HT2C receptor agonists

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

cAMP is an important messenger for ADP-induced platelet aggregation

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Adrenaline potentiates PI 3-kinase in platelets stimulated with thrombin and SFRLLN: role of secreted ADP

1 reference

https://api.crossref.org/works/10.1080%2F09537100310001612399

21 January 2018

Identifiers

10.1080/09537100310001612399

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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