(Q44724575)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14717693%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase (English)

1 reference

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17 November 2019

3

1 reference

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17 November 2019

6

Vincent G H Eijsink

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14717693%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

author name string

Bjørnar Synstad

1

1 reference

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17 November 2019

Sigrid Gåseidnes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14717693%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Gert Vriend

4

1 reference

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17 November 2019

Jens E Nielsen

5

1 reference

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17 November 2019

language of work or name

English

0 references

publication date

1 January 2004

1 reference

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17 November 2019

1 reference

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17 November 2019

volume

271

1 reference

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17 November 2019

issue

2

1 reference

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17 November 2019

page(s)

253-262

1 reference

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Structural and sequence-based classification of glycoside hydrolases

17 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Stereochemical course of the hydrolysis reaction catalyzed by chitinases A1 and D from Bacillus circulans WL-12.

21 January 2018

1 reference

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The X-ray structure of a chitinase from the pathogenic fungus Coccidioides immitis

21 January 2018

1 reference

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Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

The 1.8 A resolution structure of hevamine, a plant chitinase/lysozyme, and analysis of the conserved sequence and structure motifs of glycosyl hydrolase family 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

The third chitinase gene (chiC) of Serratia marcescens 2170 and the relationship of its product to other bacterial chitinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Roles of the exposed aromatic residues in crystalline chitin hydrolysis by chitinase A from Serratia marcescens 2170.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Mechanism of catalysis by retaining beta-glycosyl hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

21 January 2018

1 reference

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X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

NAG-thiazoline, An N -Acetyl-β-hexosaminidase Inhibitor That Implicates Acetamido Participation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Structural insights into the catalytic mechanism of a family 18 exo-chitinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

High resolution structural analyses of mutant chitinase A complexes with substrates provide new insight into the mechanism of catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Site-directed mutagenesis and functional analysis of active site acidic amino acid residues D142, D144 and E146 in Manduca sexta (tobacco hornworm) chitinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: mimicry of carbohydrate substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

On the evaluation and optimization of protein X-ray structures for pKa calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

WHAT IF: a molecular modeling and drug design program

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Optimizing the hydrogen-bond network in Poisson-Boltzmann equation-based pK(a) calculations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Calculating pKa values in enzyme active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

The structure of an allosamidin complex with the Coccidioides immitis chitinase defines a role for a second acid residue in substrate-assisted mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Chitinase and beta-1,3-glucanase in the lutoid-body fraction of Hevea latex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

The pKa of the general acid/base carboxyl group of a glycosidase cycles during catalysis: a 13C-NMR study of bacillus circulans xylanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X

Structure of the D140N mutant of chitinase B fromSerratia marcescensat 1.45 Å resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2003.03923.X