(Q44727142)

5 December 2017

title

Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function (English)

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Sphingosine kinase 1 Dmel_CG1747

5 December 2017

0 references

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Sphingosine kinase 2 Dmel_CG32484

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Deron R. Herr

1

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5 December 2017

Henrik Fyrst

2

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5 December 2017

Michael B Creason

3

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5 December 2017

Van H Phan

4

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5 December 2017

Julie D Saba

5

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5 December 2017

Greg L Harris

6

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5 December 2017

language of work or name

English

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publication date

13 January 2004

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Journal of Biological Chemistry

5 December 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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5 December 2017

volume

279

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5 December 2017

issue

13

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5 December 2017

page(s)

12685-12694

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Sphingosine 1-phosphate signaling: providing cells with a sense of direction

5 December 2017

cites work

1 reference

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Downstream signalling events regulated by phosphatidylinositol 3-kinase activity

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Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions

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Phosphatidylinositol 3-kinase and the control of endosome dynamics: new players defined by structural motifs

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Diacylglycerol kinases: emerging downstream regulators in cell signaling systems.

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Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways

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Sphingosine kinase, sphingosine-1-phosphate, and apoptosis

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Sphingosine kinases: a novel family of lipid kinases

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Sphingosine-1-phosphate: an enigmatic signalling lipid

21 January 2018

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Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants

21 January 2018

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Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins

21 January 2018

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Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells

21 January 2018

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Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling

21 January 2018

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Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase

21 January 2018

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The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases

21 January 2018

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Molecular cloning and functional characterization of murine sphingosine kinase

21 January 2018

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Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution

21 January 2018

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The nucleotide-binding site of human sphingosine kinase 1

21 January 2018

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N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide.

21 January 2018

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Functional characterization of human sphingosine kinase-1

21 January 2018

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Cell type-specific localization of sphingosine kinase 1a in human tissues

21 January 2018

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PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

21 January 2018

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Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation.

21 January 2018

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Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes

21 January 2018

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

21 January 2018

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Sphingosine kinase transmits estrogen signaling in human breast cancer cells.

21 January 2018

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Sphingosine kinase: a mediator of vital cellular functions

21 January 2018

1 reference

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Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis

21 January 2018

1 reference

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Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases

21 January 2018

1 reference

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A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development

21 January 2018

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Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

21 January 2018

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Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

21 January 2018

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Sply regulation of sphingolipid signaling molecules is essential for Drosophila development

21 January 2018

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Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans

21 January 2018

1 reference

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De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs

21 January 2018

1 reference

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Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster

21 January 2018

1 reference

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The Drosophila gene collection: identification of putative full-length cDNAs for 70% of D. melanogaster genes

21 January 2018

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Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.

21 January 2018

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The SREBP pathway in Drosophila: regulation by palmitate, not sterols

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M310647200

Distribution of sphingosine kinase activity in mouse tissues: contribution of SPHK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Metabolism of sphingosine 1-phosphate and lysophosphatidic acid: a genome wide analysis of gene expression in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Characterization of sphingolipid long-chain base kinase in Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

Purification and characterization of rat kidney sphingosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310647200

21 January 2018

Identifiers

DOI

10.1074/JBC.M310647200

1 reference

5 December 2017

1 reference