(Q34459677)

2 August 2017

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title

Phosphatidylinositol 3-kinase and the control of endosome dynamics: new players defined by structural motifs (English)

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2 August 2017

Corvera S

1

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2 August 2017

publication date

1 December 2001

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2 August 2017

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2 August 2017

volume

2

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2 August 2017

issue

12

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2 August 2017

page(s)

859-866

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

2 August 2017

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PI3-kinase inhibition: a target for drug development?

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Synthesis and function of 3-phosphorylated inositol lipids

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Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

21 January 2018

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Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis

21 January 2018

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Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking

21 January 2018

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Endocytosis and vesicular trafficking of immune complexes and activation of phospholipase D by the human high-affinity IgG receptor requires distinct phosphoinositide 3-kinase activities

21 January 2018

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Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin

21 January 2018

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Wortmannin retards the movement of the mannose 6-phosphate/insulin-like growth factor II receptor and its ligand out of endosomes

21 January 2018

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Disruption of GLUT1 glucose carrier trafficking in L6E9 and Sol8 myoblasts by the phosphatidylinositol 3-kinase inhibitor wortmannin

21 January 2018

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Trafficking kinetics of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes

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Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells

21 January 2018

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Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway.

21 January 2018

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Wortmannin inhibits transcytosis of dimeric IgA by the polymeric immunoglobulin receptor

21 January 2018

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Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells

21 January 2018

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Evidence for apical endocytosis in polarized hepatic cells: phosphoinositide 3-kinase inhibitors lead to the lysosomal accumulation of resident apical plasma membrane proteins

21 January 2018

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Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity

21 January 2018

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Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities

21 January 2018

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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

21 January 2018

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Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger

21 January 2018

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FYVE fingers bind PtdIns(3)P

21 January 2018

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A functional PtdIns(3)P-binding motif

21 January 2018

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EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

21 January 2018

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The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization

21 January 2018

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EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

21 January 2018

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The Rab5 effector EEA1 interacts directly with syntaxin-6

21 January 2018

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Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

21 January 2018

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A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic

21 January 2018

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Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells

21 January 2018

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Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

21 January 2018

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Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

21 January 2018

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Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

21 January 2018

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PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin

21 January 2018

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Hrs-2 regulates receptor-mediated endocytosis via interactions with Eps15

21 January 2018

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Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate

21 January 2018

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The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

21 January 2018

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SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Phox homology domains specifically bind phosphatidylinositol phosphates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Identification of a family of sorting nexin molecules and characterization of their association with receptors

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Identification and characterization of SNX15, a novel sorting nexin involved in protein trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Overexpression of a novel sorting nexin, SNX15, affects endosome morphology and protein trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

The myotubularin family: from genetic disease to phosphoinositide metabolism

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

PTEN and myotubularin: novel phosphoinositide phosphatases

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Mammalian inositol polyphosphate 5-phosphatase II can compensate for the absence of all three yeast Sac1-like-domain-containing 5-phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Phosphatidylinositol 3′-kinase, But Not p70 Ribosomal S6 Kinase, Is Involved in Membrane Protein Recycling: Wortmannin Inhibits Glucose Transport and Downregulates Cell-Surface Transferrin Receptor Numbers Independently of Any Effect on Fluid-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Wortmannin-sensitive Trafficking Pathways in Chinese Hamster Ovary Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Early endosomal localization of hrs requires a sequence within the proline- and glutamine-rich region but not the FYVE finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

Neutrophil signal transduction and activation of the respiratory burst

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

Enhanced degradation of EGF receptors by a sorting nexin, SNX1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0854.2001.21201.X

7 January 2021

10.1034/J.1600-0854.2001.21201.X

Identifiers

DOI

1 reference

2 August 2017

1 reference