(Q44736078)

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Increased anticholinergic challenge-induced memory impairment associated with the APOE-epsilon4 allele in the elderly: a controlled pilot study

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Europe PubMed Central

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5 December 2017

Increased anticholinergic challenge-induced memory impairment associated with the APOE-epsilon4 allele in the elderly: a controlled pilot study (English)

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Europe PubMed Central

PubMed publication ID

5 December 2017

1

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5 December 2017

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John J Sidtis

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5 December 2017

author name string

Lisa M Willoughby

2

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5 December 2017

Keith Wesnes

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5 December 2017

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publication date

1 February 2004

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5 December 2017

Neuropsychopharmacology

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5 December 2017

29

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5 December 2017

2

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5 December 2017

403-409

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Europe PubMed Central

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5 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.npp.1300305

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Cognitive and other adverse effects of diphenhydramine use in hospitalized older patients

1 reference

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Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

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Normalizing counts and cerebral blood flow intensity in functional imaging studies of the human brain.

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No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice.

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E4 allele dosage does not predict cholinergic activity or synapse loss in Alzheimer's disease

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Cholinergic markers in elderly patients with early signs of Alzheimer disease.

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Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

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21 January 2018

Metrifonate treatment of AD: influence of APOE genotype.

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Hypersensitivity to scopolamine in the elderly

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Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury

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Comparison of central and peripheral pharmacologic effects of biperiden and trihexyphenidyl in human volunteers.

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Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain

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Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease

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Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease

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Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group.

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21 January 2018

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

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Anticholinergic sensitivity in patients with dementia of the Alzheimer type and age-matched controls. A dose-response study

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Nicotinic receptors, muscarinic receptors and choline acetyltransferase activity in the temporal cortex of Alzheimer patients with differing apolipoprotein E genotypes.

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Age-related decline in central cholinergic function demonstrated with scopolamine.

1 reference

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The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease.

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Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

1 reference

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ApoE as a prognostic factor for post–traumatic coma

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ApoE genotype and survival from intracerebral haemorrhage

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300305

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based on heuristic

inferred from DOI database lookup

Cholinergic markers in Alzheimer disease

1 reference

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Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture

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based on heuristic

inferred from DOI database lookup

Increased cognitive sensitivity to scopolamine with age and a perspective on the scopolamine model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300305

7 January 2021

based on heuristic

inferred from DOI database lookup

A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein epsilon 4 allele

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300305

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of muscarinic receptor blockers on the turnover rate of acetylcholine in various regions of the rat brain

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inferred from DOI database lookup

Identifiers

10.1038/SJ.NPP.1300305

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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