(Q44754423)

6 December 2017

Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity (English)

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6 December 2017

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5

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6 December 2017

4

Manfred T Reetz

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6 December 2017

Marco Bocola

1

1 reference

PubMed ID

14760743

6 December 2017

Nikolaj Otte

series ordinal

2

1 reference

PubMed ID

14760743

6 December 2017

Karl-Erich Jaeger

series ordinal

3

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6 December 2017

1 February 2004

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6 December 2017

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6 December 2017

5

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6 December 2017

214-223

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6 December 2017

2

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Directed Evolution and Biocatalysis

6 December 2017

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

DNA polymerase fidelity and the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Enantioselective enzymes for organic synthesis created by directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Tinkering with enzymes: what are we learning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Insights into enzyme function from studies on mutants of dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Subtilisin--an enzyme designed to be engineered

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Engineering new functions and altering existing functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Improved enantioselectivity of a lipase by rational protein engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Directed evolution converts subtilisin E into a functional equivalent of thermitase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Directed molecular evolution of cytochrome c peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Effects of remote mutation on the autolysis of HIV-1 PR: X-ray and NMR investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Network of coupled promoting motions in enzyme catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

How enzymes adapt: lessons from directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Mutations in distant residues moderately increase the enantioselectivity of Pseudomonas fluorescens esterase towards methyl 3bromo-2-methylpropanoate and ethyl 3phenylbutyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

The crystal structure of Bacillus subtilis lipase: a minimal alpha/beta hydrolase fold enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Directed evolution of an esterase from Pseudomonas fluorescens. Random mutagenesis by error-prone PCR or a mutator strain and identification of mutants showing enhanced enantioselectivity by a resorufin-based fluorescence assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Lipases as practical biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Density-functional exchange-energy approximation with correct asymptotic behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Molecular modeling of the enantioselectivity in lipase-catalyzed transesterification reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Stereoselectivity of Pseudomonas cepacia lipase toward secondary alcohols: a quantitative model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

A molecular mechanism of enantiorecognition of tertiary alcohols by carboxylesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

MAB, a generally applicable molecular force field for structure modelling in medicinal chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

All-atom empirical potential for molecular modeling and dynamics studies of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Green Fluorescent Proteins: Empirical Force Field for the Neutral and Deprotonated Forms of the Chromophore. Molecular Dynamics Simulations of the Wild Type and S65T Mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Directed evolution of an enantioselective lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

New methods for the high-throughput screening of enantioselective catalysts and biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Lipases: Interfacial Enzymes with Attractive Applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Rational design of Rhizopus oryzae lipase with modified stereoselectivity toward triradylglycerols

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Computer simulations of enantioselective ester hydrolyses catalyzed by Pseudomonas cepacia lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

A quantitative model for predicting enzyme enantioselectivity: application to Burkholderia cepacia lipase and 3-(aryloxy)-1,2-propanediol derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Structural and energetic determinants for enantiopreferences in kinetic resolution of lipases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Tech.Sight. Modeling--a tool for experimentalists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

Charge distribution from a simple molecular orbital type calculation and non-bonding interaction terms in the force field MAB

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200300731

21 January 2018

Identifiers

DOI

10.1002/CBIC.200300731

1 reference

6 December 2017

1 reference

PubMed ID

14760743