(Q44757357)

English

N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines

scientific article published in May 2004

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scholarly article

1 reference

Europe PubMed Central

6 December 2017

N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines (English)

1 reference

Europe PubMed Central

6 December 2017

1 reference

based on heuristic

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author name string

Cuello M

1

1 reference

Europe PubMed Central

6 December 2017

Coats AO

2

1 reference

Europe PubMed Central

6 December 2017

Darko I

3

1 reference

Europe PubMed Central

6 December 2017

Ettenberg SA

4

1 reference

Europe PubMed Central

6 December 2017

Gardner GJ

5

1 reference

Europe PubMed Central

6 December 2017

Nau MM

6

1 reference

Europe PubMed Central

6 December 2017

Liu JR

7

1 reference

Europe PubMed Central

6 December 2017

Birrer MJ

8

1 reference

Europe PubMed Central

6 December 2017

Lipkowitz S

9

1 reference

Europe PubMed Central

6 December 2017

publication date

1 May 2004

1 reference

Europe PubMed Central

6 December 2017

Cell Death & Differentiation

1 reference

Europe PubMed Central

6 December 2017

11

1 reference

Europe PubMed Central

6 December 2017

527-541

1 reference

Europe PubMed Central

6 December 2017

5

1 reference

Europe PubMed Central

6 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401387

0 references

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

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7 January 2021

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Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Fenretinide and its relation to cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoids and ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoic acid receptor beta expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

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Mechanism of fenretinide (4-HPR)-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis by fenretinide (4HPR) in human ovarian carcinoma cells and its association with retinoic acid receptor expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting ceramide metabolism--a strategy for overcoming drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Sensitization of human ovarian tumor cells by subtoxic CDDP to anti-fas antibody-mediated cytotoxicity and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Combination effect of anti-Fas antibody and chemotherapeutic drugs in ovarian cancer cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical pathways of retinoid transport, metabolism, and signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of Retinoidal Actions by Diazepinylbenzoic Acids.1Retinoid Synergists Which Activate the RXR−RAR Heterodimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoid X receptor-antagonistic diazepinylbenzoic acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-xL inhibits cytochrome c release but not mitochondrial depolarization during the activation of multiple death pathways by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 oncoprotein protects the human prostatic carcinoma cell line PC3 from TRAIL-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Lethal effect of the anti-Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenovirus-mediated p53 growth inhibition of ovarian cancer cells is independent of endogenous p53 status

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Prolonged wild-type p53 protein accumulation and cisplatin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

The machinery of programmed cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of retinoic acid receptor overexpression in sensitivity to fenretinide and tumorigenicity of human ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401387

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CDD.4401387

1 reference

Europe PubMed Central

6 December 2017

1 reference

Europe PubMed Central

6 December 2017

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