(Q44767296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14968298%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

title

Non-esterified fatty acids are deleterious for human pancreatic islet function at physiological glucose concentration (English)

1 reference

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23 November 2019

0 references

0 references

10

1 reference

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23 November 2019

Ghaffar Muharram

5

1 reference

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Marie-Christine Vantyghem

23 November 2019

8

1 reference

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23 November 2019

author name string

M Dubois

1

1 reference

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23 November 2019

J Kerr-Conte

2

1 reference

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23 November 2019

V Gmyr

3

1 reference

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23 November 2019

T Bouckenooghe

4

1 reference

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23 November 2019

M D'Herbomez

6

1 reference

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23 November 2019

A Martin-Ponthieu

7

1 reference

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23 November 2019

B Vandewalle

9

1 reference

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23 November 2019

publication date

13 February 2004

1 reference

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23 November 2019

1 reference

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23 November 2019

volume

47

1 reference

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23 November 2019

issue

3

1 reference

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23 November 2019

page(s)

463-469

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00125-004-1347-1

23 November 2019

exact match

0 references

cites work

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Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function

21 January 2018

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Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

21 January 2018

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Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

21 January 2018

1 reference

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Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration

21 January 2018

1 reference

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Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

21 January 2018

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Antecedent hyperglycemia, not hyperlipidemia, is associated with increased islet triacylglycerol content and decreased insulin gene mRNA level in Zucker diabetic fatty rats

21 January 2018

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Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats

21 January 2018

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Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia

21 January 2018

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Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal homeobox

21 January 2018

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Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

21 January 2018

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Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1).

21 January 2018

1 reference

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Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1.

21 January 2018

1 reference

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

21 January 2018

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Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression

21 January 2018

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Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells

21 January 2018

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Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor-α Gene in the Pancreatic β-Cell

21 January 2018

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Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

21 January 2018

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Automated method for isolation of human pancreatic islets

21 January 2018

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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

21 January 2018

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Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM.

21 January 2018

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Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

21 January 2018

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Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

21 January 2018

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Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function

21 January 2018

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Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase

21 January 2018

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Fatty acid metabolism and insulin secretion in pancreatic beta cells

21 January 2018

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Fatty acid regulation of gene transcription

21 January 2018

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Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells

21 January 2018

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Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

21 January 2018

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12 December 2020

Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years.

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12 December 2020

Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels

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12 December 2020

Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release

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12 December 2020

Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor alpha (PPARalpha)-independent pathway

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12 December 2020

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12 December 2020

Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose

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12 December 2020

Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells

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12 December 2020

A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation

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12 December 2020

Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1).

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12 December 2020

What if Minkowski had been ageusic? An alternative angle on diabetes

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12 December 2020

The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

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12 December 2020