(Q44778500)

6 December 2017

title

Antagonism of GxxPG fragments ameliorates manifestations of aortic disease in Marfan syndrome mice (English)

1 reference

6 December 2017

1 reference

1 reference

9

1 reference

6 December 2017

Angelika Pletschacher

6

object named as

Angelika Pletschacher

0 references

Yskert von Kodolitsch

7

object named as

Yskert von Kodolitsch

0 references

author name string

Gao Guo

1

1 reference

6 December 2017

Begoña Muñoz-García

2

1 reference

6 December 2017

Claus-Eric Ott

3

1 reference

6 December 2017

Johannes Grünhagen

4

1 reference

6 December 2017

Shaaban A Mousa

5

1 reference

6 December 2017

Angelika Pletschacher

6

1 reference

6 December 2017

Petra Knaus

8

1 reference

6 December 2017

publication date

24 October 2012

1 reference

6 December 2017

published in

Human Molecular Genetics

1 reference

6 December 2017

volume

22

1 reference

6 December 2017

issue

3

1 reference

6 December 2017

page(s)

433-443

1 reference

Marfan syndrome: an update of genetics, medical and surgical management

6 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Mutations of FBN1 and genotype-phenotype correlations in Marfan syndrome and related fibrillinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

A Gly --> Ser change causes defective folding in vitro of calcium-binding epidermal growth factor-like domains from factor IX and fibrillin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Differential effect of FBN1 mutations on in vitro proteolysis of recombinant fibrillin-1 fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Mutations in calcium-binding epidermal growth factor modules render fibrillin-1 susceptible to proteolysis. A potential disease-causing mechanism in Marfan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

The molecular pathogenesis of the Marfan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

A G1127S change in calcium-binding epidermal growth factor-like domain 13 of human fibrillin-1 causes short range conformational effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Consequences of cysteine mutations in calcium-binding epidermal growth factor modules of fibrillin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Structural consequences of cysteine substitutions C1977Y and C1977R in calcium-binding epidermal growth factor-like domain 30 of human fibrillin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

The molecular genetics of Marfan syndrome and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: biochemical and computational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Induction of macrophage chemotaxis by aortic extracts from patients with Marfan syndrome is related to elastin binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Elastin fragments drive disease progression in a murine model of emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

A function for the macrophage F4/80 molecule in tolerance induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

p38 MAPK is an early determinant of promiscuous Smad2/3 signaling in the aortas of fibrillin-1 (Fbn1)-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Epigenetic control of vascular smooth muscle cells in Marfan and non-Marfan thoracic aortic aneurysms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms, and sporadic aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Alterations of beta-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF-beta(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Fibrillin-1 regulates the bioavailability of TGFbeta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS439

21 January 2018

Identifiers

DOI

10.1093/HMG/DDS439

1 reference

6 December 2017

1 reference