(Q44803765)

6 December 2017

title

Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis (English)

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6 December 2017

Matthew B Nodwell

1

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6 December 2017

Helge Menz

series ordinal

2

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6 December 2017

Stefan F Kirsch

series ordinal

3

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6 December 2017

Stephan A Sieber

series ordinal

4

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6 December 2017

publication date

31 May 2012

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6 December 2017

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6 December 2017

volume

13

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6 December 2017

issue

10

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6 December 2017

page(s)

1439-1446

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Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa

6 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer

21 January 2018

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Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

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Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms.

21 January 2018

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Mechanism-based profiling of enzyme families

21 January 2018

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Activity based probes for proteases: applications to biomarker discovery, molecular imaging and drug screening.

21 January 2018

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Mechanism of the cobalt oxazoline palladacycle (COP)-catalyzed asymmetric synthesis of allylic esters.

21 January 2018

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Catalytic asymmetric synthesis of chiral allylic esters

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.201200265

Mu50 glycopeptide-resistant Staphylococcus aureus: the case of the missing penicillinase.

21 January 2018

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Cu-catalyzed azide-alkyne cycloaddition

21 January 2018

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

21 January 2018

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Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition

21 January 2018

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Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria

21 January 2018

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Protein reactivity of natural product-derived γ-butyrolactones

21 January 2018

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Methionine sulfoxide reductases and virulence of bacterial pathogens

21 January 2018

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Peptide methionine sulfoxide reductase contributes to the maintenance of adhesins in three major pathogens

21 January 2018

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Peptide methionine sulfoxide reductase (MsrA) is a virulence determinant in Mycoplasma genitalium

21 January 2018

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Transcription Profiling of the mgrA Regulon in Staphylococcus aureus

21 January 2018

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Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus

21 January 2018

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Targeting MgrA-mediated virulence regulation in Staphylococcus aureus

21 January 2018

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Two active forms of UDP-N-acetylglucosamine enolpyruvyl transferase in gram-positive bacteria

21 January 2018

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The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors

21 January 2018

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Thiamin biosynthesis in prokaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?

21 January 2018

1 reference

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Identification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Both thiamine uptake and biosynthesis of thiamine precursors are required for intracellular replication of Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Identification of small molecule inhibitors of pyruvate kinase M2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Proteomic profiling of metalloprotease activities with cocktails of active-site probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

Stereoselective Synthesis of Both Enantiomers of Rugulactone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200265

21 January 2018

Identifiers

DOI

10.1002/CBIC.201200265

1 reference

6 December 2017

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