(Q44840283)

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Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity.

scientific article published on 12 April 2004

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27 December 2019

Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity (English)

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27 December 2019

Saccharomyces cerevisiae

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Daniel José Moreno Fernández Ayala

4

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27 December 2019

Guillermo López-Lluch

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27 December 2019

C Santos-Ocaña

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27 December 2019

Catherine F. Clarke

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Catherine F Clarke

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27 December 2019

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Sergio Padilla

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27 December 2019

Tanya Jonassen

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27 December 2019

María A Jiménez-Hidalgo

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27 December 2019

Beth Marbois

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27 December 2019

Plácido Navas

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27 December 2019

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12 April 2004

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27 December 2019

Journal of Biological Chemistry

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27 December 2019

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27 December 2019

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27 December 2019

25995-26004

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27 December 2019

New concepts on the role of ubiquinone in the mitochondrial respiratory chain

1 reference

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21 January 2018

Acyl-CoA dehydrogenases, electron transfer flavoprotein and electron transfer flavoprotein dehydrogenase

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21 January 2018

Divergent evolution of pyrimidine biosynthesis between anaerobic and aerobic yeasts

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21 January 2018

Biochemical, physiological and medical aspects of ubiquinone function

1 reference

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21 January 2018

Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport

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21 January 2018

Requirement for coenzyme Q in plasma membrane electron transport

1 reference

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21 January 2018

The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Genetic evidence for a multi-subunit complex in the O-methyltransferase steps of coenzyme Q biosynthesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Yeast Coq5 C-methyltransferase is required for stability of other polypeptides involved in coenzyme Q biosynthesis

1 reference

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21 January 2018

The Saccharomyces cerevisiae COQ6 Gene Encodes a Mitochondrial Flavin-dependent Monooxygenase Required for Coenzyme Q Biosynthesis

1 reference

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21 January 2018

Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

1 reference

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21 January 2018

Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Ubiquinone (coenzyme Q) biosynthesis in Escherichia coli: identification of the ubiF gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis

1 reference

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21 January 2018

Complementation of Escherichia coli ubiF mutation by Caenorhabditis elegans CLK-1, a product of the longevity gene of the nematode worm.

1 reference

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21 January 2018

The genetics of caloric restriction in Caenorhabditis elegans

1 reference

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21 January 2018

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Reproductive Fitness and Quinone Content of Caenorhabditis elegans clk-1 Mutants Fed Coenzyme Q Isoforms of Varying Length

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Redox regulation of germline and vulval development in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Quinones in long-lived clk-1 mutants of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Biochemical and evolutionary aspects of anaerobically functioning mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Null mutants of Saccharomyces cerevisiae Cu,Zn superoxide dismutase: characterization and spontaneous mutation rates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast coq mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

The Nuclear ABC1 Gene is Essential for the Correct Conformation and Functioning of the Cytochrome bc1 Complex and the Neighbouring Complexes II and IV in the Mitochondrial Respiratory Chain

1 reference

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21 January 2018

The role of charged amino acids in the alpha1-beta4 loop of the iron-sulfur protein of the cytochrome bc1 complex of yeast mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Suppression mechanisms: themes from variations

1 reference

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21 January 2018

Impact of the six nucleotides downstream of the stop codon on translation termination

1 reference

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21 January 2018

Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Mitochondrial superoxide decreases yeast survival in stationary phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Energy conservation by bifurcated electron-transfer in the cytochrome-bc1 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

EPR studies of the mitochondrial alternative oxidase. Evidence for a diiron carboxylate center

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

Mitochondrial respiratory electron carriers are involved in oxidative stress during heat stress in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400001200

21 January 2018

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

1 reference

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21 January 2018

Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration

1 reference

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21 January 2018

Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis

1 reference

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21 January 2018

Aerobic respiration in mutants of Escherichia coli accumulating quinone analogues of ubiquinone

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Metabolic control analysis of the bc1 complex of Saccharomyces cerevisiae: effect on cytochrome c oxidase, respiration and growth rate

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Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and non-mitochondrial sites

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Molecular mechanism of maternal rescue in the clk-1 mutants of Caenorhabditis elegans

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Rates of behavior and aging specified by mitochondrial function during development

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A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

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Silencing of ubiquinone biosynthesis genes extends life span inCaenorhabditis elegans

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A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore

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Identifiers

10.1074/JBC.M400001200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15078893%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15078893%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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