(Q44886532)

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Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys

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scholarly article

1 reference

Europe PubMed Central

7 December 2017

Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys (English)

1 reference

Europe PubMed Central

7 December 2017

author name string

Debie J Hoivik

1

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Europe PubMed Central

7 December 2017

Charles W Qualls

2

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Europe PubMed Central

7 December 2017

Rosanna C Mirabile

3

1 reference

Europe PubMed Central

7 December 2017

Neal F Cariello

4

1 reference

Europe PubMed Central

7 December 2017

Carie L Kimbrough

5

1 reference

Europe PubMed Central

7 December 2017

Heidi M Colton

6

1 reference

Europe PubMed Central

7 December 2017

Steven P Anderson

7

1 reference

Europe PubMed Central

7 December 2017

Michael J Santostefano

8

1 reference

Europe PubMed Central

7 December 2017

Ronda J Ott Morgan

9

1 reference

Europe PubMed Central

7 December 2017

Ray R Dahl

10

1 reference

Europe PubMed Central

7 December 2017

Alan R Brown

11

1 reference

Europe PubMed Central

7 December 2017

Zhiyang Zhao

12

1 reference

Europe PubMed Central

7 December 2017

Paul N Mudd

13

1 reference

Europe PubMed Central

7 December 2017

William B Oliver

14

1 reference

Europe PubMed Central

7 December 2017

H Roger Brown

15

1 reference

Europe PubMed Central

7 December 2017

Richard T Miller

16

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Europe PubMed Central

7 December 2017

language of work or name

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publication date

6 May 2004

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Europe PubMed Central

7 December 2017

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Europe PubMed Central

7 December 2017

25

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Europe PubMed Central

7 December 2017

1757-1769

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Europe PubMed Central

7 December 2017

9

1 reference

Europe PubMed Central

7 December 2017

The carcinogenicity of dietary di(2-ethylhexyl) phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Peroxisome proliferation and hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Lack of genotoxic activity of di(2-ethylhexyl)phthalate (DEHP) in rat and human hepatocytes.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Mutagenicity study of nine monoalkyl phthalates and a dialkyl phthalate using Salmonella typhimurium and Escherichia coli

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Effects of Di-2-ethylhexyl phthalate (DEHP) on gap-junctional intercellular communication (GJIC), DNA synthesis, and peroxisomal beta oxidation (PBOX) in rat, mouse, and hamster liver.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Receptor-mediated hepatocarcinogenesis: role of hepatocyte proliferation and apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Evidence for cross talk between PPARalpha and p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Role of hepatic non-parenchymal cells in the response of rat hepatocytes to the peroxisome proliferator nafenopin in vitro

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFalpha signaling

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Differential activation of hepatic NF-kappaB in rats and hamsters by the peroxisome proliferators Wy-14,643, gemfibrozil, and dibutyl phthalate.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta1 gene expression in the rat, Syrian hamster and guinea pig.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Role of thyroid hormones in hepatic effects of peroxisome proliferators

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Reversibility and persistence of di-2-ethylhexyl phthalate (DEHP)- and phenobarbital-induced hepatocellular changes in rodents

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

PPAR alpha and the regulation of cell division and apoptosis.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Differential proto-oncogene mRNA induction from rats treated with peroxisome proliferators.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Activation of immediate-early gene expression by peroxisome proliferators in vitro

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Effect of some peroxisome proliferators on transforming growth factor-beta 1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Fibrate treatment does not modify the expression of acyl coenzyme A oxidase in human liver

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Microbodies in experimentally altered cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

PPARalpha agonist-induced rodent tumors: modes of action and human relevance

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans?

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor ex

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Peroxisomal lipid metabolism.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Hepatic peroxisome proliferation in rodents and its significance for humans

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Practical stereological methods for morphometric cytology

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Correlated morphometric and biochemical studies on the liver cell. I. Morphometric model, stereologic methods, and normal morphometric data for rat liver

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

The Ki-67 protein: from the known and the unknown

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Catalase in vitro

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

The influence of renal insufficiency and haemodialysis on the kinetics of ciprofibrate

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Clinical pharmacokinetics of fibric acid derivatives (fibrates).

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Biochemical mechanisms of induction of hepatic peroxisome proliferation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Regulation of p21waf1/cip1 expression by intracellular redox conditions

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Effect on the expression of c-met, c-myc and PPAR-alpha in liver and liver tumors from rats chronically exposed to the hepatocarcinogenic peroxisome proliferator WY-14,643.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Hepatic expression of polymerase beta, Ref-1, PCNA, and Bax in WY 14,643-exposed rats and hamsters

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Induction of fatty acid beta-oxidation and peroxisome proliferation in the liver of rhesus monkeys by DL-040, a new hypolipidemic agent

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

c-Myc target genes involved in cell growth, apoptosis, and metabolism

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

c-MYC: more than just a matter of life and death

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Cyclin D-dependent kinases, INK4 inhibitors and cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Proliferation of peroxisomes without simultaneous induction of the peroxisomal fatty acid beta-oxidation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGH182

21 January 2018

Identifiers

10.1093/CARCIN/BGH182

1 reference

Europe PubMed Central

7 December 2017

1 reference

Europe PubMed Central

7 December 2017

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