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Cyclin D-dependent kinases, INK4 inhibitors and cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Cyclin D-dependent kinases, INK4 inhibitors and cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
author
Marcos Malumbres
object named as
Marcos Malumbres
series ordinal
2
0 references
author name string
Sagrario Ortega
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
Mariano Barbacid
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
language of work or name
English
0 references
publication date
1 March 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
volume
1602
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
page(s)
73-87
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
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Pathways governing G1/S transition and their response to DNA damage
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7 January 2021
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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
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Crossref
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Analysis of cyclin D3-cdk4 complexes in fibroblasts expressing and lacking p27(kip1) and p21(cip1).
1 reference
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A family of human cdc2-related protein kinases
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7 January 2021
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Identification of G1 kinase activity for cdk6, a novel cyclin D partner
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Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase
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7 January 2021
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Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression
1 reference
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Crossref
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7 January 2021
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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for cyclin-dependent kinases in cell cycle control
1 reference
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Crossref
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The D-type cyclins and their role in tumorigenesis
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 is a nuclear protein required for cell cycle progression in G1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 provides a link between development and oncogenesis in the retina and breast.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cell cycle regulator potentially involved in genesis of many tumor types
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ARF/p53 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirements for cell cycle arrest by p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of p16 in human mammary epithelial cells by CpG island methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor suppressor protein p16INK4a.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the INK4a locus in tumor suppression and cell mortality.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p14(ARF) in replicative and induced senescence of human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
INK4d-deficient mice are fertile despite testicular atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of an Rb mutation in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Invasive melanoma in Cdk4-targeted mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
To cycle or not to cycle: a critical decision in cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene amplification and overexpression of CDK4 in sporadic breast carcinomas is associated with high tumor cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of p16, RB, CDK4, and p53 gene deletion and amplification by fluorescence in situ hybridization in 96 gliomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chromosome 7q translocations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations associated with familial melanoma impair p16INK4 function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The INK4 family of cell cycle inhibitors in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 and human neoplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 in parathyroid disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific protection against breast cancers by cyclin D1 ablation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibition and cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preclinical and clinical development of cyclin-dependent kinase modulators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of cyclin-dependent kinase 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-dependent kinases: inhibition and substrate recognition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in antitumor strategies: modulation of cell cycle or differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of cyclin-dependent kinase 6 (cdk6) and frequent loss of CD44 in nasal-nasopharyngeal NK/T-cell lymphomas: comparison with CD56-negative peripheral T-cell lymphomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900037-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0304-419X(02)00037-9
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
PubMed ID
11960696
1 reference
stated in
Europe PubMed Central
PubMed ID
11960696
retrieved
3 August 2017
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